Anti-Semaphorin 5A抗体(ab70981)

概述

  • 产品名称Anti-Semaphorin 5A抗体
    参阅全部 Semaphorin 5A 一抗
  • 描述
    兔多克隆抗体to Semaphorin 5A
  • 经测试应用适用于: WB, ELISAmore details
  • 种属反应性
    与反应: Mouse, Human
  • 免疫原

    a KLH conjugated synthetic peptide selected from the C-terminal region of mouse Semaphorin 5A

性能

应用

Our Abpromise guarantee covers the use of ab70981 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/50 - 1/100. Detects a band of approximately 100 kDa (predicted molecular weight: 120 kDa).
ELISA 1/1000.

靶标

  • 相关性Members of the semaphorin protein family are involved in axonal guidance during neural development. Semaphorin 5a is thought to have a bifunctional role in axon guidance, exerting both attractive and inhibitory effects on developing axons associated with limbic function. The thrombospondin repeats of Semaphorin 5a physically interact with both heparan sulfate proteoglycans and chondroitin sulfate proteoglycans, inducing attractive and inhibitory guidance cues, respectively. The biological responses to Semaphorin 5a are induced through binding to its high-affinity receptor, plexin B3, triggering intracellular signaling through Met.
  • 细胞定位Membrane; single-pass type I membrane protein
  • 数据库链接
  • 别名
    • SEMA5A antibody
    • SEMAF antibody
    • Semaphorin F antibody

Anti-Semaphorin 5A antibody 图像

  • Anti-Semaphorin 5A antibody (ab70981) at 1/60 dilution + mouse brain lysate at 35 µg

    Predicted band size : 120 kDa
    Observed band size : 100 kDa (why is the actual band size different from the predicted?)
    Additional bands at : 80 kDa,95 kDa. We are unsure as to the identity of these extra bands.

Anti-Semaphorin 5A antibody (ab70981)参考文献

ab70981 has not yet been referenced specifically in any publications.

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