Anti-Semaphorin 3A抗体(ab45376)

概述

  • 产品名称Anti-Semaphorin 3A抗体
    参阅全部 Semaphorin 3A 一抗
  • 描述
    兔多克隆抗体to Semaphorin 3A
  • 特异性ab45376 detects a 95kDa protein corresponding to the apparent molecular mass of Semaphorin 3A on SDS-PAGE immunoblots of human recombinant Sema3A/Fc chimera. This antibody has not been shown to be reactive in neonatal rat brain, but has weak reactivity in adult mouse brain.
  • 经测试应用适用于: WB, ELISAmore details
  • 种属反应性
    与反应: Mouse, Rat, Human
  • 免疫原

    Synthetic peptide to human Semaphorin 3A (coupled to carrier protein) corresponding to amino acids in the N-terminal region.

  • 阳性对照
    • Human recombinant Sema3A/Fc chimera.

性能

应用

Our Abpromise guarantee covers the use of ab45376 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/1000. Detects a band of approximately 95 kDa (predicted molecular weight: 89 kDa).
ELISA 1/2000.

靶标

  • 相关性One family of inhibitory axon guidance molecules is the semaphorins. The semaphorins include secreted, transmembrane, and GPI anchored extracellular molecules that are involved in regulating axon guidance by inhibiting axons from growing toward incorrect targets. Semaphorin 3A (Sema3A) may play a particularly interesting role in limiting axon regeneration since it is expressed in meningeal fibroblasts that invade the injured spinal cord and surround the glial scar. In addition, the Sema3A co receptors, Neuropilin 1 and Plexin A1, are expressed on axons that regenerate up to the injured region, but do not cross this Sema3A containing region. Thus, Sema3A and its co receptors may have important roles in regulating axon guidance during neuronal development and after neuronal injury.
  • 细胞定位Secreted
  • 数据库链接
  • 别名
    • Coll 1 antibody
    • Coll1 antibody
    • HH16 antibody
    • Hsema I antibody
    • Hsema III antibody
    • Sema domain immunoglobulin domain (Ig) short basic domain secreted (semaphorin) 3A antibody
    • Sema III antibody
    • SEMA1 antibody
    • SEMA1-PEN antibody
    • SEMA3A antibody
    • SEMAD antibody
    • SEMAIII antibody
    • SEMAL antibody
    • Semaphorin 3A precursor antibody
    • Semaphorin III antibody
    • Semaphorin like growth cone guidance homolog of chick collapsin antibody
    • Semaphorin3A antibody
    • SemD antibody
    see all

Anti-Semaphorin 3A antibody (ab45376)参考文献

ab45376 has not yet been referenced specifically in any publications.

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