Anti-Sema6A抗体- C-terminal (ab72369)


  • 产品名称
    Anti-Sema6A抗体- C-terminal
    参阅全部 Sema6A 一抗
  • 描述
    兔多克隆抗体to Sema6A - C-terminal
  • 经测试应用
    适用于: WB, ELISA, IHC-Pmore details
  • 种属反应性
    与反应: Mouse, Human
  • 免疫原

    Synthetic peptide from the C-terminal region of human Sema6A conjugated to KLH

  • 阳性对照
    • Mouse cerebellum tissue lysate.



Our Abpromise guarantee covers the use of ab72369 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/50 - 1/100. Detects a band of approximately 97 kDa (predicted molecular weight: 114 kDa).
ELISA 1/1000.
IHC-P 1/10 - 1/50.


  • 功能
    Cell surface receptor for PLXNA2 that plays an important role in cell-cell signaling. Required for normal granule cell migration in the developing cerebellum. Promotes reorganization of the actin cytoskeleton and plays an important role in axon guidance in the developing central nervous system. Can act as repulsive axon guidance cue. Has repulsive action towards migrating granular neurons. May play a role in channeling sympathetic axons into the sympathetic chains and controlling the temporal sequence of sympathetic target innervation.
  • 序列相似性
    Belongs to the semaphorin family.
    Contains 1 PSI domain.
    Contains 1 Sema domain.
  • 细胞定位
    Cell membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • HT018 antibody
    • SEM6A_HUMAN antibody
    • SEMA antibody
    • Sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A antibody
    • Sema Q antibody
    • Sema VIA antibody
    • SEMA6A 1 antibody
    • Sema6a antibody
    • SEMA6A-1 antibody
    • SEMA6A1 antibody
    • Semaphorin 6A 1 antibody
    • Semaphorin Q antibody
    • Semaphorin VIA antibody
    • Semaphorin-6A antibody
    • Semaphorin-6A-1 antibody
    • SEMAQ antibody
    • VIA antibody
    see all

Anti-Sema6A antibody - C-terminal 图像

  • All lanes : Anti-Sema6A antibody - C-terminal (ab72369) at 1/50 dilution

    Lane 1 : Mouse cerebellum tissue lysate
    Lane 2 : Mouse cerebellum tissue lysate with blocking peptide

    Lysates/proteins at 12.5 µg per lane.

    Predicted band size : 114 kDa
    Observed band size : 97 kDa (why is the actual band size different from the predicted?)
  • ab72369 at 1/50 dilution staining Sema6A - C - terminal in human brain tissue section by Immunohistochemistry (Formalin/ PFA fixed paraffin-embedded sections). A peroxidase conjugated secondary antibody was used followed by DAB staining.

Anti-Sema6A antibody - C-terminal (ab72369)参考文献

This product has been referenced in:
  • Lee MY  et al. Differential expression of centrosome regulators in Her2+ breast cancer cells versus non-tumorigenic MCF10A cells. Cell Div 9:3 (2014). WB ; Human . Read more (PubMed: 25278993) »
  • Sabag AD  et al. The role of the plexin-A2 receptor in Sema3A and Sema3B signal transduction. J Cell Sci 127:5240-52 (2014). Read more (PubMed: 25335892) »

See all 2 Publications for this product

Product Wall

Thank you for your enquiry and interest in our products.

I can confirm that this product (ab72369: Anti-Sema6A antibody - C-terminal) was launched in 2008.

If you need any further assistance in the future, please do not hesitate to ...

Read More