概述

  • 产品名称Anti-SELS抗体- Aminoterminal end
    参阅全部 SELS 一抗
  • 描述
    兔多克隆抗体to SELS - Aminoterminal end
  • 经测试应用适用于: WB, ELISAmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat
  • 免疫原

    Synthetic peptide corresponding to N-terminal residues of human SELS

性能

应用

Our Abpromise guarantee covers the use of ab58656 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 21 kDa.
ELISA Use at an assay dependent dilution.

靶标

  • 相关性Involved in the degradation process of misfolded endoplasmic reticulum (ER) luminal proteins. Participates in the transfer of misfolded proteins from the ER to the cytosol, where they are destroyed by the proteasome in a ubiquitin dependent manner. Probably acts by serving as a linker between DERL1, which mediates the retrotranslocation of misfolded proteins into the cytosol, and the ATPase complex VCP, which mediates the translocation and ubiquitination.
  • 细胞定位Endoplasmic reticulum; endoplasmic reticulum membrane; single pass membrane protein.
  • 数据库链接
  • 别名
    • AD-015 antibody
    • ADO15 antibody
    • MGC104346 antibody
    • MGC2553 antibody
    • SBBI8 antibody
    • selenoprotein S antibody
    • SEPS1 antibody
    • VCP interacting membrane protein antibody
    • VCP-interacting membrane antibody
    • VIMP antibody
    see all

Anti-SELS antibody - Aminoterminal end (ab58656)参考文献

This product has been referenced in:
  • Schoenmakers E  et al. Mutations in the selenocysteine insertion sequence-binding protein 2 gene lead to a multisystem selenoprotein deficiency disorder in humans. J Clin Invest 120:4220-35 (2010). WB ; Human . Read more (PubMed: 21084748) »

See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"