Anti-SELS抗体- Aminoterminal end (ab58656)
- 数据表
- 具体的参考文献 (1)
- 实验方案
概述
-
产品名称Anti-SELS抗体- Aminoterminal end
参阅全部 SELS 一抗 -
描述兔多克隆抗体to SELS - Aminoterminal end
-
宿主Rabbit
-
经测试应用适用于: WB, ELISAmore details
-
种属反应性与反应: Human
预测可用于: Mouse, Rat
-
免疫原
Synthetic peptide corresponding to N-terminal residues of human SELS
性能
-
形式Liquid
-
存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
-
存储溶液Preservative: 0.01% Sodium Azide
Constituents: 50% Glycerol, PBS -
Concentration information loading... -
纯度Immunogen affinity purified
-
克隆多克隆
-
同种型IgG
-
研究领域
相关产品
-
Compatible Secondaries
应用
Our Abpromise guarantee covers the use of ab58656 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| 应用 | Ab评论 | 说明 |
|---|---|---|
| WB | Use a concentration of 1 µg/ml. Predicted molecular weight: 21 kDa. | |
| ELISA | Use at an assay dependent dilution. |
靶标
-
相关性Involved in the degradation process of misfolded endoplasmic reticulum (ER) luminal proteins. Participates in the transfer of misfolded proteins from the ER to the cytosol, where they are destroyed by the proteasome in a ubiquitin dependent manner. Probably acts by serving as a linker between DERL1, which mediates the retrotranslocation of misfolded proteins into the cytosol, and the ATPase complex VCP, which mediates the translocation and ubiquitination.
-
细胞定位Endoplasmic reticulum; endoplasmic reticulum membrane; single pass membrane protein.
-
数据库链接
- Entrez Gene: 55829 Human
- Entrez Gene: 109815 Mouse
- Entrez Gene: 286900 Rat
- Omim: 607918 Human
- SwissProt: Q9BQE4 Human
- SwissProt: Q9BCZ4 Mouse
- SwissProt: Q8VHV8 Rat
- Unigene: 32148 Human
-
别名
- AD-015 antibody
- ADO15 antibody
- MGC104346 antibody
see all
文献
This product has been referenced in:
- Schoenmakers E et al. Mutations in the selenocysteine insertion sequence-binding protein 2 gene lead to a multisystem selenoprotein deficiency disorder in humans. J Clin Invest 120:4220-35 (2010). WB ; Human . Read more (PubMed: 21084748) »
客户评价及客户问答
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"