Anti-SELS抗体- Aminoterminal end (ab58656)

概述

• 产品名称
  Anti-SELS抗体- Aminoterminal end
  参阅全部 SELS 一抗
• 描述
  兔多克隆抗体to SELS - Aminoterminal end
• 经测试应用
  适用于: WB, ELISAmore details
• 种属反应性
  与反应: Human
  预测可用于: Mouse, Rat
• 免疫原

  Synthetic peptide corresponding to N-terminal residues of human SELS

性能

• 形式
  Liquid
• 存放说明
  Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
• 存储溶液
  Preservative: 0.01% Sodium Azide
  Constituents: 50% Glycerol, PBS
• Concentration information loading...
• 纯度
  Immunogen affinity purified
• 克隆
  多克隆
• 同种型
  IgG
• 研究领域
  • Immunology
  • Innate Immunity
  • Macrophage / Inflamm.

  • Signal Transduction
  • Protein Trafficking
  • ER Proteins

相关产品

• Compatible Secondaries
  • Goat Anti-Rabbit IgG H&L (Alexa Fluor® 488) (ab150077)
  • Goat Anti-Rabbit IgG H&L (HRP) (ab205718)

应用

靶标

• 相关性
  Involved in the degradation process of misfolded endoplasmic reticulum (ER) luminal proteins. Participates in the transfer of misfolded proteins from the ER to the cytosol, where they are destroyed by the proteasome in a ubiquitin dependent manner. Probably acts by serving as a linker between DERL1, which mediates the retrotranslocation of misfolded proteins into the cytosol, and the ATPase complex VCP, which mediates the translocation and ubiquitination.
• 细胞定位
  Endoplasmic reticulum; endoplasmic reticulum membrane; single pass membrane protein.
• 数据库链接
  • Entrez Gene: 55829 Human
  • Entrez Gene: 109815 Mouse
  • Entrez Gene: 286900 Rat
  • Omim: 607918 Human
  • SwissProt: Q9BQE4 Human
  • SwissProt: Q9BCZ4 Mouse
  • SwissProt: Q8VHV8 Rat
  • Unigene: 32148 Human
• 别名
  • AD-015 antibody
  • ADO15 antibody
  • MGC104346 antibody

  • MGC2553 antibody
  • SBBI8 antibody
  • selenoprotein S antibody
  • SEPS1 antibody
  • VCP interacting membrane protein antibody
  • VCP-interacting membrane antibody
  • VIMP antibody

  see all

实验方案

• Western blot protocols