概述

  • 产品名称Anti-SELS抗体
    参阅全部 SELS 一抗
  • 描述
    小鼠多克隆抗体to SELS
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Full length human SELS protein (NP_060915.2).

  • 阳性对照
    • A431 cell lysate. Cell lysate from transfected 293T cells.

性能

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应用

Our Abpromise guarantee covers the use of ab89760 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 µg/ml. Detects a band of approximately 21 kDa (predicted molecular weight: 21 kDa).

靶标

  • 相关性Involved in the degradation process of misfolded endoplasmic reticulum (ER) luminal proteins. Participates in the transfer of misfolded proteins from the ER to the cytosol, where they are destroyed by the proteasome in a ubiquitin dependent manner. Probably acts by serving as a linker between DERL1, which mediates the retrotranslocation of misfolded proteins into the cytosol, and the ATPase complex VCP, which mediates the translocation and ubiquitination.
  • 细胞定位Endoplasmic reticulum; endoplasmic reticulum membrane; single pass membrane protein.
  • 数据库链接
  • 别名
    • AD-015 antibody
    • ADO15 antibody
    • MGC104346 antibody
    • MGC2553 antibody
    • SBBI8 antibody
    • selenoprotein S antibody
    • SEPS1 antibody
    • VCP interacting membrane protein antibody
    • VCP-interacting membrane antibody
    • VIMP antibody
    see all

Anti-SELS antibody 图像

  • Anti-SELS antibody (ab89760) at 1 µg/ml + A431 cell lysate at 50 µg
    Developed using the ECL technique

    Predicted band size : 21 kDa
    Observed band size : ~20 kDa (why is the actual band size different from the predicted?)
  • All lanes : Anti-SELS antibody (ab89760) at 1 µg/ml

    Lane 1 : cell lysate from SELS transfected 293T cells
    Lane 2 : cell lysate from non transfected 293T cells

    Lysates/proteins at 25 µg per lane.

    Developed using the ECL technique

    Predicted band size : 21 kDa
    Observed band size : 20 kDa (why is the actual band size different from the predicted?)

Anti-SELS antibody (ab89760)参考文献

ab89760 has not yet been referenced specifically in any publications.

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