概述

  • 产品名称Anti-Selenoprotein M抗体[10C1]
    参阅全部 Selenoprotein M 一抗
  • 描述
    小鼠单克隆抗体[10C1] to Selenoprotein M
  • 经测试应用适用于: ELISA, WB, IPmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Recombinant full length protein (Human) purified from E coli

性能

应用

Our Abpromise guarantee covers the use of ab16960 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ELISA
WB
IP
  • 应用说明ELISA: Use at an assay dependent dilution.
    IP: Use at a concentration of 1 - 2 µg/ml lysates.
    WB: 1/2000. Predicted molecular weight: 16 kDa.

    Not tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 相关性Selenoprotein M is widely expressed and expressed highly in the mammalian brain. It is localized to the perinuclear structures (Golgi/ER). A growing body of evidence relates selenium to cancer prevention, immune system function, male fertility, cardiovascular disorder, control of the aging and neurodiseases process. Selenoproteins are thought to be responsible for the majority of these biomedical effects of selenium. Approximately 17 selenoproteins have been identified until now. Although the function of many selenoproteins are unknown, some play important roles in antioxidant mechanisms. It has been also implicated in the regulation of signaling pathways through catalysis of thiol/disulfide exchange. The roles of Selenoprotein M have not been clearly identified until present time.
    • 细胞定位Cytoplasm; perinuclear region. Endoplasmic reticulum Probable. Golgi apparatus Probable. Note: Localized to perinuclear structures corresponding to Golgi and endoplasmic reticulum.
    • 数据库链接
    • 别名
      • Selenoprotein M antibody
      • Selenoprotein SelM antibody
      • SELM antibody
      • SelM protein antibody
      • SEPM antibody
      see all

    Anti-Selenoprotein M antibody [10C1] (ab16960)参考文献

    This product has been referenced in:
    • Xu G  et al. The relationship between deiodinase activity and inflammatory responses under the stimulation of uremic toxins. J Transl Med 12:239 (2014). WB ; Human . Read more (PubMed: 25174507) »
    • Goo JS  et al. Proteomic analysis of kidneys from selenoprotein M transgenic rats in response to increased bioability of selenium. Clin Proteomics 10:10 (2013). WB ; Rat . Read more (PubMed: 23937859) »

    See all 2 Publications for this product

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