Anti-Selenium Binding Protein 1抗体(ab80868)

概述

  • 产品名称Anti-Selenium Binding Protein 1抗体
    参阅全部 Selenium Binding Protein 1 一抗
  • 描述
    兔多克隆抗体to Selenium Binding Protein 1
  • 经测试应用适用于: IHC-P, WBmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat, Rabbit, Horse, Chicken, Guinea pig, Cow, Cat, Dog, Zebrafish
  • 免疫原

    Synthetic peptide (Human)

  • 阳性对照
    • 721_B cell lysate

性能

应用

Our Abpromise guarantee covers the use of ab80868 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P 1/100.
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 44 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

靶标

  • 功能Selenium-binding protein which may be involved in the sensing of reactive xenobiotics in the cytoplasm. May be involved in intra-Golgi protein transport.
  • 组织特异性Highly expressed in liver, lung, colon, prostate, kidney and pancreas. In brain, present both in neurons and glia (at protein level). Down-regulated in lung adenocarcinoma, colorectal carcinoma and ovarian cancer. Two-fold up-regulated in brain and blood from schizophrenia patients.
  • 序列相似性Belongs to the selenium-binding protein family.
  • 翻译后修饰Phosphorylated.
    The N-terminus is blocked.
  • 细胞定位Nucleus. Cytoplasm > cytosol. Membrane. May associate with Golgi membrane. May associate with the membrane of autophagosomes.
  • Information by UniProt
  • 数据库链接
  • 别名
    • 56 kDa selenium binding protein antibody
    • 56 kDa selenium-binding protein antibody
    • hSBP antibody
    • LPSB antibody
    • SBP antibody
    • SBP1 antibody
    • SBP1_HUMAN antibody
    • SBP56 antibody
    • Selenbp1 antibody
    • Selenbp2 antibody
    • Selenium binding protein 2 antibody
    • Selenium binding protein1 antibody
    • Selenium-binding protein 1 antibody
    • SELNBP1 antibody
    • SP56 antibody
    see all

Anti-Selenium Binding Protein 1 antibody 图像

  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of human lung tissue labelling Selenium Binding Protein 1 with ab80868 at 1/100. A Cy3-conjugated donkey anti-rabbit IgG (1/200) was used as the secondary antibody. Positive staining shown in the cytoplasm. membrane and nuclei of alveolar type I and II cells. Magnification: 20X. Exposure time: 0.5 - 2.0 seconds. Left - DAPI. Middle - Selenium Binding Protein 1. Right - Merge.
  • Anti-Selenium Binding Protein 1 antibody (ab80868) at 1 µg/ml + 721_B cell lysate at 10 µg

    Secondary
    HRP conjugated anti-Rabbit IgG at 1/100000 dilution
    Developed using the ECL technique

    Predicted band size : 44 kDa
    Observed band size : 44 kDa

Anti-Selenium Binding Protein 1 antibody (ab80868)参考文献

ab80868 has not yet been referenced specifically in any publications.

Product Wall

Thank you for contacting us. I had a look at the AP56 protein in mouse which is the selenium liver binding protein in mouse, this appears to be a different target. I did not see an alternative name for AP56 on the Swiss Prot page, but the molecular wei...

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