概述

  • 产品名称Anti-Securin 2抗体
    参阅全部 Securin 2 一抗
  • 描述
    兔多克隆抗体to Securin 2
  • 经测试应用适用于: WB, ELISAmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rabbit, Horse, Cow, Cat, Dog, Pig, Chimpanzee
  • 免疫原

    Synthetic peptide, corresponding to a region within internal sequence amino acids 73-122 (SVKTNGPRKQKQPSFSAKKMTEKTVKTKSSVPASDDAYPEIEKFFPFNL L) of Human Securin 2, NP_006598

  • 阳性对照
    • HepG2 cell lysate.

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • 存储溶液Preservative: None
    Constituents: 2% Sucrose, PBS
  • Concentration information loading...
  • 纯度Immunogen affinity purified
  • 纯化说明ab81181 is purified by a peptide affinity chromatography method.
  • 克隆多克隆
  • 同种型IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab81181 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 µg/ml. Detects a band of approximately 21 kDa (predicted molecular weight: 21 kDa). Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.
ELISA Use at an assay dependent concentration.

ELISA titre using peptide based assay: 1/312500.

靶标

  • 组织特异性Expressed at low levels in the pituitary, liver, spleen, prostate, testis, ovary, small intestine and colon. Also expressed in various pituitary, testicular, liver and ovarian tumors.
  • 序列相似性Belongs to the securin family.
  • 结构域The N-terminal destruction box (D-box) acts as a recognition signal for degradation via the ubiquitin-proteasome pathway.
  • 细胞定位Cytoplasm. Nucleus.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Pituitary tumor transforming 2 antibody
    • Pituitary tumor transforming gene 2 protein antibody
    • Pituitary tumor-transforming gene 2 protein antibody
    • PTTG2 antibody
    • PTTG2_HUMAN antibody
    • Securin-2 antibody
    see all

Anti-Securin 2 antibody 图像

  • Anti-Securin 2 antibody (ab81181) at 1 µg/ml + HepG2 cell lysate at 10 µg

    Secondary
    HRP conjugated anti-Rabbit IgG at 1/50000 dilution

    Predicted band size : 21 kDa
    Observed band size : 26 kDa (why is the actual band size different from the predicted?)

Anti-Securin 2 antibody (ab81181)参考文献

ab81181 has not yet been referenced specifically in any publications.

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