Anti-SECISBP2抗体[2957C2a] (ab70601)

概述

  • 产品名称Anti-SECISBP2抗体[2957C2a]
    参阅全部 SECISBP2 一抗
  • 描述
    小鼠单克隆抗体[2957C2a] to SECISBP2
  • 经测试应用适用于: WB, Dot blotmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Recombinant fragment of human SECISBP2 derived from a near N terminal internal sequence.

  • 阳性对照
    • HEK293 whole cell lysate.

性能

相关产品

应用

Our Abpromise guarantee covers the use of ab70601 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 0.2 - 2 µg/ml. Detects a band of approximately 100 kDa (predicted molecular weight: 95 kDa).
Dot blot Use at an assay dependent dilution.

靶标

  • 功能Binds to the SECIS element in the 3'-UTR of some mRNAs encoding selenoproteins. Binding is stimulated by SELB.
  • 组织特异性Expressed at high levels in testis.
  • 疾病相关Defects in SECISBP2 are a cause of abnormal thyroid hormone metabolism (ATHYHM) [MIM:609698]. This phenotype is associated with a reduction in type II iodothyronine deiodinase activity.
  • 细胞定位Nucleus.
  • Information by UniProt
  • 数据库链接
  • 别名
    • DKFZp686C09169 antibody
    • OTTHUMP00000064929 antibody
    • OTTHUMP00000064930 antibody
    • OTTHUMP00000064931 antibody
    • OTTHUMP00000064932 antibody
    • RP11 89K14.1 antibody
    • SBP 2 antibody
    • SBP2 antibody
    • SEBP2_HUMAN antibody
    • SECIS binding protein 2 antibody
    • SECIS-binding protein 2 antibody
    • SECISBP 2 antibody
    • SECISBP2 antibody
    • Selenocysteine insertion sequence binding protein 2 antibody
    • Selenocysteine insertion sequence-binding protein 2 antibody
    see all

Anti-SECISBP2 antibody [2957C2a] 图像

  • Anti-SECISBP2 antibody [2957C2a] (ab70601) at 2 µg/ml + HEK293 whole cell lysate at 25 µg
    Developed using the ECL technique

    Predicted band size : 95 kDa
    Observed band size : 105 kDa (why is the actual band size different from the predicted?)

Anti-SECISBP2 antibody [2957C2a] (ab70601)参考文献

ab70601 has not yet been referenced specifically in any publications.

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