概述

  • 产品名称Anti-SEC63抗体
    参阅全部 SEC63 一抗
  • 描述
    小鼠多克隆抗体to SEC63
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Full length SEC63 protein (Human) (NP_009145.1).

  • 阳性对照
    • Human pancreas lysate, SEC63 transfected 293T cell lysate.

性能

应用

Our Abpromise guarantee covers the use of ab68550 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/500 - 1/1000. Detects a band of approximately 88 kDa (predicted molecular weight: 88 kDa).

靶标

  • 相关性SEC63 and SEC62 proteins are found to be associated with the ribosome-free SEC61 complex, which is the central component of the protein translocation apparatus of the endoplasmic reticulum (ER) membrane. It is speculated that Sec61-Sec62-Sec63 may perform post-translational protein translocation into the ER. The Sec61-Sec62-Sec63 complex might also perform the backward transport of ER proteins that are subject to the ubiquitin-proteasome-dependent degradation pathway. Mutations in SEC63 cause autosomal dominant polycystic liver disease.
  • 细胞定位Endoplasmic reticulum membrane; Multi pass membrane protein.
  • 数据库链接
  • 别名
    • ERdj2 antibody
    • PRO2507 antibody
    • SEC 63 antibody
    • SEC63L antibody
    • Translocation protein SEC63 homolog antibody
    see all

Anti-SEC63 antibody 图像

  • Anti-SEC63 antibody (ab68550) at 1/500 dilution + Human pancreas lysate at 50 µg

    Secondary
    Goat Anti-Mouse IgG (H&L) at 1/2500 dilution

    Predicted band size : 88 kDa
    Observed band size : 88 kDa
  • All lanes : Anti-SEC63 antibody (ab68550) at 1/500 dilution

    Lane 1 : SEC63 transfected 293T cell lysate
    Lane 2 : Non-transfected 293T cell lysate

    Lysates/proteins at 25 µg per lane.

    Secondary
    Goat Anti-Mouse IgG (H&L) at 1/2500 dilution

    Predicted band size : 88 kDa
    Observed band size : 88 kDa

Anti-SEC63 antibody (ab68550)参考文献

ab68550 has not yet been referenced specifically in any publications.

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