The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Use a concentration of 1 µg/ml. Predicted molecular weight: 38 kDa.
功能Regulatory protein which represses transcription and augments histone deacetylase activity of HDAC1. May have a potential role in tumor suppressor pathways (By similarity). May function in the assembly and/or enzymatic activity of the mSin3A corepressor complex or in mediating interactions between the complex and other regulatory complexes.
组织特异性Expressed in various cancer cell ines.
序列相似性Belongs to the SDS3 family.
结构域The C-terminus is involved in transcriptional repression by HDAC-independent mechanisms.