概述

  • 产品名称Anti-SDS3抗体
    参阅全部 SDS3 一抗
  • 描述
    山羊多克隆抗体to SDS3
  • 经测试应用适用于: WB, IPmore details
  • 种属反应性
    与反应: Mouse, Human
    预测可用于: Rabbit, Chicken, Guinea pig, Cow, Dog, Turkey, Pig, Xenopus laevis, Chimpanzee, Zebrafish, Rhesus monkey, Gorilla, Orangutan, Xenopus tropicalis
  • 免疫原

    Synthetic peptide (Human) - which represented a portion of human Suppressor of Defective Silencing 3 encoded in part by exons 7 and 8.

  • 阳性对照
    • HeLa cell lysate.

性能

应用

Our Abpromise guarantee covers the use of ab3740 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/1000 - 1/5000. Predicted molecular weight: 45 kDa.
IP Use at an assay dependent dilution. PubMed: 21239494

靶标

  • 功能Regulatory protein which represses transcription and augments histone deacetylase activity of HDAC1. May have a potential role in tumor suppressor pathways (By similarity). May function in the assembly and/or enzymatic activity of the mSin3A corepressor complex or in mediating interactions between the complex and other regulatory complexes.
  • 组织特异性Expressed in various cancer cell ines.
  • 序列相似性Belongs to the SDS3 family.
  • 结构域The C-terminus is involved in transcriptional repression by HDAC-independent mechanisms.
  • Information by UniProt
  • 数据库链接
  • 别名
    • 2400003N08Rik antibody
    • 2410008L21Rik antibody
    • 45 kDa Sin3 associated polypeptide antibody
    • 45 kDa Sin3-associated polypeptide antibody
    • AU067672 antibody
    • FLJ00052 antibody
    • MGC104711 antibody
    • mSds3 antibody
    • RGD1305986 antibody
    • SAP45 antibody
    • SDS3 antibody
    • SDS3, yeast, homolog of antibody
    • SDS3_HUMAN antibody
    • Sin3 histone deacetylase corepressor complex component SDS3 antibody
    • Sin3A associated protein 45kDa antibody
    • Suds3 antibody
    • Suppressor of defective silencing 3 antibody
    • Suppressor of defective silencing 3 homolog (S cerevisiae) antibody
    • Suppressor of defective silencing 3 homolog (SDS3 S cerevisiae) antibody
    • Suppressor of defective silencing 3 protein homolog antibody
    see all

Anti-SDS3 antibody 图像



  • Predicted band size : 45 kDa


    Sample: HeLa whole cell lysate (50µg/lane)

    Antibody: Affinity purified Goat anti-SDS 3 (ab3740) used at the concentrations indicated.

    Detection: ECL exposed for 2 minutes.

Anti-SDS3 antibody (ab3740)参考文献

This product has been referenced in:
  • Ramakrishna S  et al. Hyaluronan Binding Motifs of USP17 and SDS3 Exhibit Anti-Tumor Activity. PLoS One 7:e37772 (2012). WB ; Human . Read more (PubMed: 22662218) »
  • Ramakrishna S  et al. K63 specific deubiquitination of SDS3 by USP17 regulates HDAC activity. J Biol Chem : (2011). IP ; Human . Read more (PubMed: 21239494) »

See all 2 Publications for this product

Product Wall

There are currently no Abreviews or Questions for ab3740.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"