The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
应用说明WB: 1/500 - 1/1000. Detects a band of approximately 41 kDa.
Detection Antibody Pair.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
功能Plays a role in the establishment of cell polarity and epithelial lumen formation (By similarity). May play a role in ciliogenesis.
组织特异性Expressed in thymus, prostate, testis, ovary, small intestine, colon, mucosa, colon and renal cancer tumors.
疾病相关Senior-Loken syndrome 7 (SLSN7) [MIM:613615]: A renal-retinal disorder characterized by progressive wasting of the filtering unit of the kidney (nephronophthisis), with or without medullary cystic renal disease, and progressive eye disease. Typically this disorder becomes apparent during the first year of life. Note=The disease is caused by mutations affecting the gene represented in this entry.
细胞定位Cytoplasm and Cytoplasm > cytoskeleton > centrosome > centriole. Cell junction. Located at the distal ends of both centrioles and colocalizes to centrosomes throughout the cell cycle.