概述

  • 产品名称
    Anti-SCUBE1抗体
  • 描述
    兔多克隆抗体to SCUBE1
  • 特异性
    ab105358 is predicted to not crossreact with other SCUBE members.
  • 经测试应用
    适用于: ICC/IF, WB, ICCmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    A 14 amino acid peptide near the center of Human SCUBE1 (NP_766638).

  • 阳性对照
    • WB: Daudi cell lysate ICC: Daudi cells

性能

应用

Our Abpromise guarantee covers the use of ab105358 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ICC/IF Use a concentration of 20 µg/ml.
WB Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 108 kDa.
ICC Use a concentration of 20 µg/ml.

靶标

  • 功能
    Could function as an adhesive molecule and its matrix bound and soluble fragments may play a critical role in vascular biology.
  • 组织特异性
    Detected in endothelial cells. Highly expressed in platelets. Stored in platelet alpha granules, and transferrred to the cell surface upon activation and aggregation. A smaller form, probably produced by limited proteolysis, after being released from the storage granules, is associated with thrombus and localized with the subendothelial matrices in atherosclerotic plaques.
  • 序列相似性
    Contains 1 CUB domain.
    Contains 9 EGF-like domains.
  • 翻译后修饰
    N-glycosylated.
    Could be proteolytically cleaved to release a smaller active fragment.
  • 细胞定位
    Secreted. Cell membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • SCUB1_HUMAN antibody
    • SCUBE 1 antibody
    • SCUBE1 antibody
    • Signal peptide, CUB and EGF-like domain-containing protein 1 antibody
    • Signal peptide, CUB domain, EGF like 1 antibody
    see all

图片

  • Anti-SCUBE1 antibody (ab105358) at 1 µg/ml + Daudi cell lysate at 15 µg

    Predicted band size : 108 kDa
  • Immunocytochemical analysis of SCUBE1 in Daudi cells using ab105358 at 20 µg/ml.
  • Immunofluorescence of SCUBE1 in Daudi cells using ab105358 at 20 ug/ml.

文献

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