概述

  • 产品名称Anti-ScpA抗体
  • 描述
    兔多克隆抗体to ScpA
  • 经测试应用适用于: ELISA, WBmore details
  • 种属反应性
    与反应: Recombinant Fragment
    预测可用于: Staphylococcus aureus
  • 免疫原

    Synthetic peptide corresponding to C terminal residues of Staphylococcus aureus ScpA

性能

应用

Our Abpromise guarantee covers the use of ab92983 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ELISA 1/2000 - 1/5000.
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 44 kDa. for 2 hours. This antibody has been tested in Western blot against the recombinant peptide used as an immunogen. We have no data on detection of endogenous protein.

靶标

  • 相关性ScpA (Staphylococcal cysteine proteinase A) is able to degrade elastin. ScpA (Staphylococcal cysteine proteinase A) has a broad endopeptidase action on proteins including elastin, but rather limited hydrolysis of small-molecule substrates. Assays are conveniently made with hemoglobin, casein or Z-Phe-Arg-NHMec as substrate. Prematurely activated/folded staphopain A is inhibited by staphostatin A (scpB), which is probably required to protect staphylococcal cytoplasmic proteins from degradation by scpA. In the cytoplasm, prematurely activated/folded scpA forms a stable non-covalent complex with scpB. Cleavage leads to the activation of scpA probably by an auto-catalytic manner. The catalytic maturation of scpA appears to reside outside the cascade of activation started by the metalloprotease aureolysin (aur) scpA (Staphylococcal cysteine proteinaseA) belongs to the peptidase C47 family.
  • 细胞定位Secreted
  • 数据库链接
    • 别名
      • sspB2 antibody
      • sspP antibody
      • Staphopain A antibody
      • Staphylococcal cysteine proteinase A antibody
      • Staphylopain A antibody
      see all

    Anti-ScpA antibody (ab92983)参考文献

    ab92983 has not yet been referenced specifically in any publications.

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