概述

  • 产品名称
  • 描述
    兔多克隆抗体to Scn2b
  • 经测试应用
    适用于: WB, Indirect ELISAmore details
  • 种属反应性
    与反应: Rat, Recombinant fragment
    预测可用于: Human
  • 免疫原

    Synthetic peptide corresponding to N-terminal residues of Rat Scn2b

性能

  • 形式
    Liquid
  • 存放说明
    Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C.
  • 存储溶液
    Preservative: 0.01% Sodium Azide
    Constituents: 50% Glycerol, PBS
  • Concentration information loading...
  • 纯度
    Immunogen affinity purified
  • 克隆
    多克隆
  • 同种型
    IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab56205 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/500 - 1/1000. Predicted molecular weight: 24 kDa.

This antibody has been tested in Western blot against the recombinant peptide used as an immunogen. We have no data on detection of endogenous protein.

Indirect ELISA Use at an assay dependent concentration.

靶标

  • 功能
    Crucial in the assembly, expression, and functional modulation of the heterotrimeric complex of the sodium channel. The subunit beta-2 causes an increase in the plasma membrane surface area and in its folding into microvilli. Interacts with TNR may play a crucial role in clustering and regulation of activity of sodium channels at nodes of Ranvier.
  • 组织特异性
    Brain specific.
  • 序列相似性
    Belongs to the sodium channel auxiliary subunit SCN2B (TC 8.A.17) family.
    Contains 1 Ig-like C2-type (immunoglobulin-like) domain.
  • 细胞定位
    Membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Neuronal voltage gated sodium channel beta 2 subunit antibody
    • Scn 2b antibody
    • Scn2b antibody
    • SCN2B_HUMAN antibody
    • Sodium channel beta 2 subunit antibody
    • Sodium channel subunit beta 2 antibody
    • Sodium channel subunit beta-2 antibody
    • Sodium channel voltage gated type II beta antibody
    • Sodium channel voltage gated type II beta polypeptide antibody
    see all

实验方案

文献

ab56205 has not yet been referenced specifically in any publications.

客户评价及客户问答

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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