概述

  • 产品名称Anti-Scn2b抗体
    参阅全部 Scn2b 一抗
  • 描述
    兔多克隆抗体to Scn2b
  • 经测试应用适用于: WB, Indirect ELISAmore details
  • 种属反应性
    与反应: Rat, Recombinant Fragment
    预测可用于: Human
  • 免疫原

    Synthetic peptide corresponding to N-terminal residues of Rat Scn2b

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C.
  • 存储溶液Preservative: 0.01% Sodium Azide
    Constituents: 50% Glycerol, PBS
  • Concentration information loading...
  • 纯度Immunogen affinity purified
  • 克隆多克隆
  • 同种型IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab56205 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use at an assay dependent concentration. Predicted molecular weight: 24 kDa. This antibody has been tested in Western blot against the recombinant peptide used as an immunogen. We have no data on detection of endogenous protein.
Indirect ELISA Use at an assay dependent dilution.

靶标

  • 功能Crucial in the assembly, expression, and functional modulation of the heterotrimeric complex of the sodium channel. The subunit beta-2 causes an increase in the plasma membrane surface area and in its folding into microvilli. Interacts with TNR may play a crucial role in clustering and regulation of activity of sodium channels at nodes of Ranvier.
  • 组织特异性Brain specific.
  • 序列相似性Belongs to the sodium channel auxiliary subunit SCN2B (TC 8.A.17) family.
    Contains 1 Ig-like C2-type (immunoglobulin-like) domain.
  • 细胞定位Membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Neuronal voltage gated sodium channel beta 2 subunit antibody
    • Scn 2b antibody
    • Scn2b antibody
    • SCN2B_HUMAN antibody
    • Sodium channel beta 2 subunit antibody
    • Sodium channel subunit beta 2 antibody
    • Sodium channel subunit beta-2 antibody
    • Sodium channel voltage gated type II beta antibody
    • Sodium channel voltage gated type II beta polypeptide antibody
    see all

Anti-Scn2b antibody 图像

  • All lanes : Anti-Scn2b antibody (ab56205) at 1 µg/ml

    Lane 1 : HeLa (Human epithelial carcinoma cell line) Whole Cell Lysate
    Lane 2 : Caco 2 (Human colonic carcinoma cell line) Whole Cell Lysate
    Lane 3 : SW480 (Human colon adenocarcinoma cell line) Whole Cell Lysate

    Lysates/proteins at 10 µg per lane.

    Secondary
    Goat polyclonal to Rabbit IgG - H&L - Pre-Adsorbed (HRP)

    Predicted band size : 24 kDa
    Observed band size : 24 kDa
    Additional bands at : 30 kDa (possible post-translational modification).

Anti-Scn2b antibody (ab56205)参考文献

ab56205 has not yet been referenced specifically in any publications.

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