概述

  • 产品名称SCH 23390 hydrochloride
  • 描述
    Selective D1-like dopamine receptor antagonist
  • 生物学描述Selective D1-like dopamine receptor antagonist. Ki values are 0.2 (D1), 0.3 (D5), 1100 (D2), 800 (D3) and 3000 nM (D4). Some activity at 5-HT receptors (Ki values are 6.3 and 14.8 nM for 5-HT1C and 5-HT2C, respectively). Antipsychotic properties. Centrally active following subcutaneous administration.
  • 纯度> 99%

性能

    SCH 23390 hydrochloride (ab120597)参考文献

    This product has been referenced in:
    • Schlenker EH In hamsters the D1 receptor antagonist SCH23390 depresses ventilation during hypoxia. Brain Res 1187:146-53 (2008). Read more (PubMed: 18036574) »
    • Millan MJ  et al. The "selective" dopamine D1 receptor antagonist, SCH23390, is a potent and high efficacy agonist at cloned human serotonin2C receptors. Psychopharmacology (Berl) 156:58-62 (2001). Read more (PubMed: 11465634) »
    • Bourne JA SCH 23390: the first selective dopamine D1-like receptor antagonist. CNS Drug Rev 7:399-414 (2001). Read more (PubMed: 11830757) »
    • Briggs CA  et al. Activation of the 5-HT1C receptor expressed in Xenopus oocytes by the benzazepines SCH 23390 and SKF 38393. Br J Pharmacol 104:1038-44 (1991). Read more (PubMed: 1687364) »

    See 1 Publication for this product

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    SCH 23390 hydrochloride (ab120597) n’est pas vendu en solution mais en poudre qui doit être dilué dans de l’eau. Ce produit est soluble dans de l’eau jusqu’a 100 mM.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE, NOT FOR USE IN HUMANS"