SCH 23390 hydrochloride,D1-like dopamine receptor拮抗剂(ab120597)
Key features and details
- Selective D1-like dopamine receptor antagonist
- CAS Number: 125941-87-9
- Purity: > 99%
- Soluble in water to 100 mM
- Form / State: Solid
- Source: Synthetic
概述
-
产品名称
SCH 23390 hydrochloride,D1-like dopamine receptor拮抗剂 -
描述
Selective D1-like dopamine receptor拮抗剂 -
纯度
> 99% -
CAS编号
125941-87-9 -
化学结构
性能
-
化学名称
(R)-(+)-7-Chloro-8-hydroxy-3-methyl-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine hydrochloride -
分子量
324.25 -
分子式
C17H18ClNO.HCl -
PubChem识别号
11957535 -
存放说明
Store at +4°C. It is important to note that this product is reported to be light sensitive. Store In the Dark. Store under desiccating conditions. -
溶解度概述
Soluble in water to 100 mM -
处理
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
-
SMILES
CN1CCC2=CC(=C(C=C2[C@H](C1)C3=CC=CC=C3)O)Cl.Cl -
来源
Synthetic
-
研究领域
图片
实验方案
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
文献 (6)
ab120597 被引用在 6 文献中.
- Burke DA & Alvarez VA Serotonin receptors contribute to dopamine depression of lateral inhibition in the nucleus accumbens. Cell Rep 39:110795 (2022). PubMed: 35545050
- Wang L et al. A high-performance genetically encoded fluorescent indicator for in vivo cAMP imaging. Nat Commun 13:5363 (2022). PubMed: 36097007
- Xue J et al. Midbrain dopamine neurons arbiter OCD-like behavior. Proc Natl Acad Sci U S A 119:e2207545119 (2022). PubMed: 36343236
- Bocarsly ME et al. A Mechanism Linking Two Known Vulnerability Factors for Alcohol Abuse: Heightened Alcohol Stimulation and Low Striatal Dopamine D2 Receptors. Cell Rep 29:1147-1163.e5 (2019). PubMed: 31665630
- Spigolon G et al. cJun N-terminal kinase (JNK) mediates cortico-striatal signaling in a model of Parkinson's disease. Neurobiol Dis 110:37-46 (2018). PubMed: 29107639
- Iderberg H et al. Modulating mGluR5 and 5-HT1A/1B receptors to treat l-DOPA-induced dyskinesia: effects of combined treatment and possible mechanisms of action. Exp Neurol 250:116-24 (2013). PubMed: 24029003