Anti-SCGN抗体- Carboxyterminal end (ab71098)

概述

  • 产品名称Anti-SCGN抗体- Carboxyterminal end
    参阅全部 SCGN 一抗
  • 描述
    兔多克隆抗体to SCGN - Carboxyterminal end
  • 经测试应用适用于: WB, ELISA, IHC-Pmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Synthetic peptide (Human) from the C terminal region conjugated to KLH

  • 阳性对照
    • WB: CEM cell lysate IHC-P: Human lung carcinoma tissue

性能

应用

Our Abpromise guarantee covers the use of ab71098 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/50 - 1/100. Detects a band of approximately 35 kDa (predicted molecular weight: 32 kDa).
ELISA 1/1000.
IHC-P 1/50.

靶标

  • 组织特异性Expressed at high levels in the pancreatic islets of Langerhans and to a much lesser extent in the gastrointestinal tract (stomach, small intestine and colon), the adrenal medulla and cortex and the thyroid C-cells. In the brain, the expression is restricted to distinct subtypes of neurons with highest expression in the molecular layer of the cerebellum (stellate and basket cells), in the anterior part of the pituitary gland, in the thalamus, in the hypothalamus and in a subgroup of neocortical neurons.
  • 序列相似性Contains 6 EF-hand domains.
  • 细胞定位Cytoplasm. Secreted. Cytoplasmic vesicle > secretory vesicle membrane. Predominantly cytoplasmic. A small proportion is associated with secretory granules and membrane fractions (By similarity). Detectable in human serum after ischemic neuronal damage.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Calbindin like antibody
    • CALBL antibody
    • DJ501N12.8 antibody
    • OTTHUMP00000016124 antibody
    • Scgn antibody
    • SECRET antibody
    • Secretagogin antibody
    • Secretagogin EF hand calcium binding protein antibody
    • SEGN antibody
    • SEGN_HUMAN antibody
    • Setagin antibody
    see all

Anti-SCGN antibody - Carboxyterminal end 图像

  • Anti-SCGN antibody - Carboxyterminal end (ab71098) at 1/60 dilution + CEM cell lysate at 35 µg

    Predicted band size : 32 kDa
    Observed band size : 35 kDa (why is the actual band size different from the predicted?)
    Additional bands at : 45 kDa,56 kDa. We are unsure as to the identity of these extra bands.
  • Formalin fixed and paraffin embedded human lung carcinoma tissue labelled with ab71098 at 1/50 dilution to detect SCGN. ab71098 was peroxidase conjugated to the secondary antibody, followed by DAB staining.

Anti-SCGN antibody - Carboxyterminal end (ab71098)参考文献

ab71098 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab71098.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"