概述

  • 产品名称Anti-SCGN抗体
    参阅全部 SCGN 一抗
  • 描述
    兔多克隆抗体to SCGN
  • 经测试应用适用于: WB, ICC/IFmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat, Cow
  • 免疫原

    Recombinant fragment, corresponding to a region within amino acids 57-238 of Human SCGN (AAH00336).

  • 阳性对照
    • HeLa and HCT116 cells and whole cell lysates.

性能

应用

Our Abpromise guarantee covers the use of ab111871 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/500 - 1/3000. Predicted molecular weight: 32 kDa.
ICC/IF 1/100 - 1/500.

靶标

  • 组织特异性Expressed at high levels in the pancreatic islets of Langerhans and to a much lesser extent in the gastrointestinal tract (stomach, small intestine and colon), the adrenal medulla and cortex and the thyroid C-cells. In the brain, the expression is restricted to distinct subtypes of neurons with highest expression in the molecular layer of the cerebellum (stellate and basket cells), in the anterior part of the pituitary gland, in the thalamus, in the hypothalamus and in a subgroup of neocortical neurons.
  • 序列相似性Contains 6 EF-hand domains.
  • 细胞定位Cytoplasm. Secreted. Cytoplasmic vesicle > secretory vesicle membrane. Predominantly cytoplasmic. A small proportion is associated with secretory granules and membrane fractions (By similarity). Detectable in human serum after ischemic neuronal damage.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Calbindin like antibody
    • CALBL antibody
    • DJ501N12.8 antibody
    • OTTHUMP00000016124 antibody
    • Scgn antibody
    • SECRET antibody
    • Secretagogin antibody
    • Secretagogin EF hand calcium binding protein antibody
    • SEGN antibody
    • SEGN_HUMAN antibody
    • Setagin antibody
    see all

Anti-SCGN antibody 图像

  • Anti-SCGN antibody (ab111871) at 1/1000 dilution + HeLa whole cell lysate at 30 µg

    Predicted band size : 32 kDa
  • ab111871 at 1/200 dilution staining SCGN in methanol-fixed HeLa cells by Immunofluorescence. The lower image is costained with Hoechst 33342.

Anti-SCGN antibody (ab111871)参考文献

ab111871 has not yet been referenced specifically in any publications.

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