Anti-Scavenging Receptor SR-BI抗体(ab125433)

概述

  • 产品名称Anti-Scavenging Receptor SR-BI抗体
    参阅全部 Scavenging Receptor SR-BI 一抗
  • 描述
    兔多克隆抗体to Scavenging Receptor SR-BI
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rabbit, Dog
  • 免疫原

    Synthetic peptide corresponding to a region within N terminal amino acids 114-163 (LEYRTFQFQP SKSHGSESDY IVMPNILVLG AAVMMENKPM TLKLIMTLAF) of Human Scavenging Receptor SR-BI (NP_001076428; UniProt ID: F8W8N0).

  • 阳性对照
    • Human fetal kidney lysate.

应用

Our Abpromise guarantee covers the use of ab125433 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 56 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

靶标

  • 功能Receptor for different ligands such as phospholipids, cholesterol ester, lipoproteins, phosphatidylserine and apoptotic cells. Probable receptor for HDL, located in particular region of the plasma membrane, called caveolae. Facilitates the flux of free and esterified cholesterol between the cell surface and extracellular donors and acceptors, such as HDL and to a lesser extent, apoB-containing lipoproteins and modified lipoproteins. Probably involved in the phagocytosis of apoptotic cells, via its phosphatidylserine binding activity. Receptor for hepatitis C virus glycoprotein E2. Binding between SCARB1 and E2 was found to be independent of the genotype of the viral isolate. Plays an important role in the uptake of HDL cholesteryl ester.
  • 组织特异性Widely expressed.
  • 序列相似性Belongs to the CD36 family.
  • 翻译后修饰N-glycosylated.
  • 细胞定位Cell membrane. Membrane > caveola. Predominantly localized to cholesterol and sphingomyelin-enriched domains within the plasma membrane, called caveolae.
  • Information by UniProt
  • 数据库链接
  • 别名
    • CD36 and LIMPII analogous 1 antibody
    • CD36 antibody
    • CD36 Antigen like 1 antibody
    • CD36 antigen-like 1 antibody
    • CD36L1 antibody
    • CLA 1 antibody
    • CLA-1 antibody
    • CLA1 antibody
    • Collagen type I receptor antibody
    • HDLQTL6 antibody
    • MGC138242 antibody
    • SCARB1 antibody
    • Scavebger Receptor Class B Member 1 antibody
    • Scavenger receptor class B member 1 antibody
    • Scavenger Receptor Class B Type 1 antibody
    • SCRB1_HUMAN antibody
    • SR BI antibody
    • SR-BI antibody
    • SRB1 antibody
    • SRBI antibody
    • Thrombospondin receptor like 1 antibody
    • thrombospondin receptor-like 1 antibody
    see all

Anti-Scavenging Receptor SR-BI antibody 图像

  • Anti-Scavenging Receptor SR-BI antibody (ab125433) at 1 µg/ml + Human fetal kidney lysate at 10 µg

    Predicted band size : 56 kDa

Anti-Scavenging Receptor SR-BI antibody (ab125433)参考文献

ab125433 has not yet been referenced specifically in any publications.

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