概述

  • 产品名称Anti-SCARF1抗体
    参阅全部 SCARF1 一抗
  • 描述
    山羊多克隆抗体to SCARF1
  • 特异性This antibody is expected to recognise all 5 isoforms of SCARF1.
  • 经测试应用适用于: ELISA, ICC/IF, WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Synthetic peptide:

    SELDPKGQHVC

    , corresponding to amino acids 20 - 31 of Human SCARF1.

  • 阳性对照
    • Human heart lysate.

性能

应用

Our Abpromise guarantee covers the use of ab23933 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ELISA 1/32000.
ICC/IF Use at an assay dependent dilution. PubMed: 20606164
WB Use a concentration of 0.3 - 1 µg/ml. Detects a band of approximately 85-90 kDa (predicted molecular weight: 87 kDa).

靶标

  • 功能Mediates the binding and degradation of acetylated low density lipoprotein (Ac-LDL). Mediates heterophilic interactions, suggesting a function as adhesion protein. Plays a role in the regulation of neurite-like outgrowth.
  • 组织特异性Endothelial cells.
  • 序列相似性Contains 6 EGF-like domains.
  • 细胞定位Membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Acetyl LDL receptor antibody
    • Endothelial cells scavenger receptor antibody
    • SCARF1 antibody
    • Scavenger receptor class F member 1 antibody
    • Scavenger receptor expressed by endothelial cells 1 antibody
    • Scavenger receptor expressed by endothelial cells antibody
    • SREC antibody
    • SREC-I antibody
    • SREC_HUMAN antibody
    see all

Anti-SCARF1 antibody 图像

  • All lanes : Anti-SCARF1 antibody (ab23933) at 0.3 µg/ml

    Lane 1 : (A) Human Heart lysate
    Lane 2 : (B) Human Heart lysate with immunizing peptide

    Lysates/proteins at 35 µg per lane.


    Predicted band size : 87 kDa
    Observed band size : 85-90 kDa (why is the actual band size different from the predicted?)
    Additional bands at : 28 kDa (possible non-specific binding).

Anti-SCARF1 antibody (ab23933)参考文献

This product has been referenced in:
  • Narazaki M  et al. Oligo-guanosinenucleotide induces neuropilin-1 internalization in endothelial cells and inhibits angiogenesis. Blood : (2010). ICC/IF ; Human . Read more (PubMed: 20606164) »

See 1 Publication for this product

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