概述

  • 产品名称Anti-SCARA5抗体
    参阅全部 SCARA5 一抗
  • 描述
    兔多克隆抗体to SCARA5
  • 经测试应用适用于: ELISA, ICC, WB, IHC-Pmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse
  • 免疫原

    17 amino acid synthetic peptide near the carboxy terminus of Human SCARA5.

  • 阳性对照
    • Human Small Intestine tissue; Human liver tissue lysate.

性能

应用

Our Abpromise guarantee covers the use of ab118894 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ELISA Use at an assay dependent concentration.
ICC Use at an assay dependent concentration.
WB Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 54 kDa.
IHC-P Use a concentration of 5 µg/ml.

靶标

  • 功能Ferritin receptor that mediates non-transferrin-dependent delivery of iron. Mediates cellular uptake of ferritin-bound iron by stimulating ferritin endocytosis from the cell surface with consequent iron delivery within the cell. Delivery of iron to cells by ferritin is required for the development of specific cell types, suggesting the existence of cell type-specific mechanisms of iron traffic in organogenesis, which alternatively utilize transferrin or non-transferrin iron delivery pathways. Ferritin mediates iron uptake in capsule cells of the developing kidney. Binds preferrentially ferritin light chain (FTL) compared to heavy chain (FTH1).
  • 序列相似性Belongs to the SCARA5 family.
    Contains 1 collagen-like domain.
    Contains 1 SRCR domain.
  • 细胞定位Cell membrane.
  • Information by UniProt
  • 数据库链接
  • 形式There are 4 isoforms produced by alternative splicing.
  • 别名
    • FLJ23907 antibody
    • MGC45780 antibody
    • NET33 antibody
    • SCAR5_HUMAN antibody
    • SCARA 5 antibody
    • scara5 antibody
    • Scavenger receptor class A member 5 antibody
    • Scavenger receptor class A, member 5 (putative) antibody
    • Scavenger receptor class A, member 5 antibody
    • Scavenger receptor hlg antibody
    • Tesr antibody
    • Testis expressed scavenger receptor antibody
    see all

Anti-SCARA5 antibody 图像

  • Anti-SCARA5 antibody (ab118894) at 1 µg/ml + Human liver tissue lysate

    Predicted band size : 54 kDa
  • ab118894t 5µg/ml, staining SCARA5 in Formalin-fixed, Paraffin-embedded Human Small intestine tissue by Immunohistochemistry.

Anti-SCARA5 antibody (ab118894)参考文献

This product has been referenced in:
  • Liu J  et al. Suppression of SCARA5 by Snail1 is essential for EMT-associated cell migration of A549 cells. Oncogenesis 2:e73 (2013). WB . Read more (PubMed: 24061576) »

See 1 Publication for this product

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