- 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
- 存储溶液Preservative: 0.02% Sodium Azide
Constituents: 0.5% BSA, 0.5mg/ml Tris, pH 7.3
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- 纯度Ammonium Sulphate Precipitation
- 纯化说明Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Our Abpromise guarantee covers the use of
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
WB: Use at a concentration of 0.5 - 2 µg/ml. Detects a band of approximately 38 kDa (predicted molecular weight: 42.2 kDa).
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
- 功能May be involved in B-cell and macrophage adhesion processes. In B-cells, may act by coupling the B-cell receptor (BCR) to integrin activation. May play a role in src signaling pathway.
- 组织特异性Ubiquitously expressed. Present in platelets (at protein level).
- 序列相似性Belongs to the SKAP family.
Contains 1 PH domain.
Contains 1 SH3 domain.
- 结构域The SH3 domain interacts with FYB and PTK2B.
- 翻译后修饰Phosphorylated in resting platelets. Phosphorylated by FYN on Tyr-261 upon T-cell activation (Probable). Dephosphorylated on Tyr-75 by PTPN22.
Information by UniProt
- Fyn associated phosphoprotein SKAP55 homologue antibody
- MGC10411 antibody
- MGC33 antibody
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"