Mouse, Rat, Cow, Dog
, corresponding to C terminal amino acids 346-359 of Human SCAP2
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Preservative: 0.02% Sodium Azide
Constituents: 0.5% BSA, 0.5mg/ml Tris, pH 7.3
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Ammonium Sulphate Precipitation
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
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in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
||Use a concentration of 0.5 - 2 µg/ml. Detects a band of approximately 38 kDa (predicted molecular weight: 42.2 kDa).
May be involved in B-cell and macrophage adhesion processes. In B-cells, may act by coupling the B-cell receptor (BCR) to integrin activation. May play a role in src signaling pathway.
Ubiquitously expressed. Present in platelets (at protein level).
Belongs to the SKAP family.
Contains 1 PH domain.
Contains 1 SH3 domain.
The SH3 domain interacts with FYB and PTK2B.
Phosphorylated in resting platelets. Phosphorylated by FYN on Tyr-261 upon T-cell activation (Probable). Dephosphorylated on Tyr-75 by PTPN22.
Information by UniProt
- Fyn associated phosphoprotein SKAP55 homologue antibody
- MGC10411 antibody
- MGC33 antibody
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