概述

  • 产品名称Anti-SCAMP5抗体
    参阅全部 SCAMP5 一抗
  • 描述
    兔多克隆抗体to SCAMP5
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Mouse
    预测可用于: Rat, Rabbit, Horse, Chicken, Guinea pig, Cow, Cat, Dog, Human, Zebrafish
  • 免疫原

    Synthetic peptide corresponding to a region within C terminal amino acids 163-212 (VFSFIALSMV HKFYRGSGGS FSKAQEEWTT GAWKNPHVQQ AAQNAAMGAA) of Mouse SCAMP5 (NP_064666).

  • 阳性对照
    • Mouse liver lysate.

性能

应用

Our Abpromise guarantee covers the use of ab115788 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 26 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

靶标

  • 功能Required for the calcium-dependent exocytosis of signal sequence-containing cytokines such as CCL5. Probably acts in cooperation with the SNARE machinery. May play a role in accumulation of expanded polyglutamine (polyQ) protein huntingtin (HTT) in case of endoplasmic reticulum stress by inhibiting the endocytosis pathway.
  • 组织特异性Expressed both by neuronal and nonneuronal tissues. Expressed in brain, stomach, thyroid, spinal cord, lymph node, trachea, adrenal gland, bone marrow and in the different parts of brain. In thyroid tissues, it is expressed by the follicular epithelial cells. In the adrenal gland tissues it is detected in the zona fasciculate of the cortex region (at protein level).
  • 序列相似性Belongs to the SCAMP family. SCAMP5 subfamily.
  • 细胞定位Cell membrane. Golgi apparatus membrane. Golgi apparatus > trans-Golgi network membrane. Recycling endosome membrane. Cytoplasmic vesicle > secretory vesicle > synaptic vesicle membrane. Mainly localizes in Golgi apparatus membrane. Upon calcium-triggered exocytosis, it translocates to the cell membrane. Highly enriched in synaptic vesicles.
  • Information by UniProt
  • 数据库链接
  • 别名
    • AI426171 antibody
    • AW558254 antibody
    • DKFZp686L1799 antibody
    • hSCAMP5 antibody
    • MGC24969 antibody
    • Sc5 antibody
    • SCAM5_HUMAN antibody
    • Scamp5 antibody
    • Secretory carrier associated membrane protein 5 antibody
    • Secretory carrier membrane protein 5 antibody
    • Secretory carrier-associated membrane protein 5 antibody
    see all

Anti-SCAMP5 antibody 图像

  • Anti-SCAMP5 antibody (ab115788) at 1 µg/ml + Mouse liver lysate at 10 µg

    Predicted band size : 26 kDa

Anti-SCAMP5 antibody (ab115788)参考文献

ab115788 has not yet been referenced specifically in any publications.

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