Anti-Scaffold attachment factor B2抗体(ab104220)

概述

  • 产品名称
    Anti-Scaffold attachment factor B2抗体
    参阅全部 Scaffold attachment factor B2 一抗
  • 描述
    兔多克隆抗体to Scaffold attachment factor B2
  • 经测试应用
    适用于: WB, IHC-P, ICC/IFmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Recombinant protein fragment containing a sequence corresponding to a region within amino acids 351-502 of Human Scaffold attachment factor B2 (AAH25279).

  • 阳性对照
    • 293T, A431 and Jurkat cell lines. HBL435 xenograft.

性能

应用

Our Abpromise guarantee covers the use of ab104220 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/500 - 1/3000. Predicted molecular weight: 107 kDa.
IHC-P 1/100 - 1/500. Suggested antigen retrieval using heat mediated 10mM Citrate buffer or Tris-EDTA buffer ( PH8.0).
ICC/IF 1/100 - 1/200.

靶标

  • 功能
    Binds to scaffold/matrix attachment region (S/MAR) DNA. Can function as an estrogen receptor corepressor and can also inhibit cell proliferation.
  • 组织特异性
    Expressed at high levels in the CNS and at low levels in the liver. Expressed in a wide number of breast cancer cell lines.
  • 序列相似性
    Contains 1 RRM (RNA recognition motif) domain.
    Contains 1 SAP domain.
  • 翻译后修饰
    Phosphorylated upon DNA damage, probably by ATM or ATR.
  • 细胞定位
    Cytoplasm. Nucleus.
  • Information by UniProt
  • 数据库链接
  • 别名
    • DKFZP779C1727 antibody
    • HAP antibody
    • HET antibody
    • hsp27 ere tata binding antibody
    • KIAA0138 antibody
    • SAF B antibody
    • SAF B2 antibody
    • SAF-B2 antibody
    • SAFB antibody
    • SAFB1 antibody
    • SAFB2 antibody
    • SAFB2_HUMAN antibody
    • Scaffold attachment factor B2 antibody
    see all

图片

  • Anti-Scaffold attachment factor B2 antibody (ab104220) at 1/1000 dilution + A431 whole cell lysate at 30 µg

    Predicted band size : 107 kDa
  • Immunofluorescence analysis of methanol-fixed A431, using ab104220 at 1/200 dilution. Lower picture costained with Hoechst 33342.
  • Immunohistochemical analysis of paraffin-embedded HBL435 xenograft, using ab104220 at 1/100 dilution.

文献

ab104220 has not yet been referenced specifically in any publications.

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