Anti-Scaffold attachment factor B2抗体[6F7] (ab67344)

概述

  • 产品名称
    Anti-Scaffold attachment factor B2抗体[6F7]
    参阅全部 Scaffold attachment factor B2 一抗
  • 描述
    小鼠单克隆抗体[6F7] to Scaffold attachment factor B2
  • 经测试应用
    适用于: WB, IP, IHC-P, ICC/IFmore details
  • 种属反应性
    与反应: Mouse, Human
  • 免疫原

    Synthetic peptide:

    PEARDSKEDGRKF

    , corresponding to amino acids 345-357 of Human Scaffold attachment factor B2

  • 阳性对照
    • Human brain cortex tissue.

应用

Our Abpromise guarantee covers the use of ab67344 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB
IP
IHC-P
ICC/IF
  • 应用说明
    ICC/IF: Use at an assay dependent dilution.
    IHC-P: Use at a concentration of 5 µg/ml.
    IP: Use at an assay dependent dilution.
    WB: Use at an assay dependent dilution. Predicted molecular weight: 108 kDa.

    N.B. on SDS PAGE gels, Scaffold attachment factor B2 runs as an approximately 130 kDa protein. This aberrant migration is due to a large number of charged amino acid residues.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能
      Binds to scaffold/matrix attachment region (S/MAR) DNA. Can function as an estrogen receptor corepressor and can also inhibit cell proliferation.
    • 组织特异性
      Expressed at high levels in the CNS and at low levels in the liver. Expressed in a wide number of breast cancer cell lines.
    • 序列相似性
      Contains 1 RRM (RNA recognition motif) domain.
      Contains 1 SAP domain.
    • 翻译后修饰
      Phosphorylated upon DNA damage, probably by ATM or ATR.
    • 细胞定位
      Cytoplasm. Nucleus.
    • Information by UniProt
    • 数据库链接
    • 别名
      • DKFZP779C1727 antibody
      • HAP antibody
      • HET antibody
      • hsp27 ere tata binding antibody
      • KIAA0138 antibody
      • SAF B antibody
      • SAF B2 antibody
      • SAF-B2 antibody
      • SAFB antibody
      • SAFB1 antibody
      • SAFB2 antibody
      • SAFB2_HUMAN antibody
      • Scaffold attachment factor B2 antibody
      see all

    图片

    • ab67344 at 5µg/ml dilution staining Scaffold attachment factor B2 in human brain cortex by Immunohistochemistry, Formalin-fixed, Paraffin-embedded tissue.

    文献

    ab67344 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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