Anti-SAF-B2抗体[6F7] (ab67344)
Key features and details
- Mouse monoclonal [6F7] to SAF-B2
- Suitable for: IHC-P
- Reacts with: Human
- Isotype: IgG1
概述
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产品名称
Anti-SAF-B2抗体[6F7]
参阅全部 SAF-B2 一抗 -
描述
小鼠单克隆抗体[6F7] to SAF-B2 -
宿主
Mouse -
经测试应用
适用于: IHC-Pmore details -
种属反应性
与反应: Human -
免疫原
Synthetic peptide corresponding to Human SAF-B2 aa 345-357.
Sequence:PEARDSKEDGRKF
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阳性对照
- Human brain cortex tissue.
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Upon delivery aliquot. Store at -20°C. Avoid freeze / thaw cycle. -
存储溶液
pH: 7.4
Constituent: PBS -
Concentration information loading...
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纯度
Protein G purified -
克隆
单克隆 -
克隆编号
6F7 -
同种型
IgG1 -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab67344于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
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IHC-P |
说明 |
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IHC-P: Use at a concentration of 5 µg/ml.
IP: Use at an assay dependent dilution.
WB: Use at an assay dependent dilution. Predicted molecular weight: 108 kDa.
N.B. on SDS PAGE gels, Scaffold attachment factor B2 runs as an approximately 130 kDa protein. This aberrant migration is due to a large number of charged amino acid residues.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
靶标
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功能
Binds to scaffold/matrix attachment region (S/MAR) DNA. Can function as an estrogen receptor corepressor and can also inhibit cell proliferation. -
组织特异性
Expressed at high levels in the CNS and at low levels in the liver. Expressed in a wide number of breast cancer cell lines. -
序列相似性
Contains 1 RRM (RNA recognition motif) domain.
Contains 1 SAP domain. -
翻译后修饰
Phosphorylated upon DNA damage, probably by ATM or ATR. -
细胞定位
Cytoplasm. Nucleus. - Information by UniProt
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数据库链接
- Entrez Gene: 9667 Human
- Omim: 608066 Human
- SwissProt: Q14151 Human
- Unigene: 655392 Human
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别名
- DKFZP779C1727 antibody
- HAP antibody
- HET antibody
see all
图片
数据表及文件
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Datasheet download
文献 (0)
ab67344 尚未被引用在任何文献中。