概述

  • 产品名称Anti-SBEM抗体
  • 描述
    兔多克隆抗体to SBEM
  • 经测试应用适用于: IHC-Pmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    antigen sequence AQNPTTAAPA DTYPATGPAD DEAPDAETTA AATTA, corresponding to amino acids 19-53 of Human SBEM (UniProt ID: Q96DR8).

  • 阳性对照
    • Human breast tissue

性能

应用

Our Abpromise guarantee covers the use of ab122530 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P 1/20 - 1/50. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

靶标

  • 功能May play a role as marker for the diagnosis of metastatic breast cancer.
  • 组织特异性Expressed in mammary, salivary glands and prostate. Also detected in lung. Mainly expressed in cancer cell lines of breast origin. Highly expressed in lymph node-positive compared with node-negative tumors. Detected in all lymph node containing metastatic cells.
  • 翻译后修饰O-glycosylated.
  • 细胞定位Secreted. Membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • mucin like 1 antibody
    • mucin-like 1 antibody
    • Mucin-like protein 1 antibody
    • MUCL1 antibody
    • MUCL1_HUMAN antibody
    • Protein BS106 antibody
    • Small breast epithelial mucin antibody
    see all

Anti-SBEM antibody 图像

  • Immunohistochemical staining of SBEM in paraffin embedded Human breast tissue by Immunohistochemistry, using ab122530 at a 1/20 dilution. The image shows moderate cytoplasmic and extracellular positivity in glandular cells.

Anti-SBEM antibody (ab122530)参考文献

This product has been referenced in:
  • Liu L  et al. Small breast epithelial mucin tumor tissue expression is associated with increased risk of recurrence and death in triple-negative breast cancer patients. Diagn Pathol 8:71 (2013). Histology ; Human . Read more (PubMed: 23635316) »

See 1 Publication for this product

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