概述

  • 产品名称Anti-SAPS3抗体
  • 描述
    兔多克隆抗体to SAPS3
  • 经测试应用适用于: WB, IPmore details
  • 种属反应性
    与反应: Human
    预测可用于: Chimpanzee, Gorilla
  • 免疫原

    Synthetic peptide from a region between residue 743 and the C-terminus (residue 793) of human SAPS3,( NP_060782.2).

  • 阳性对照
    • Whole cell lysate from Hela cells.

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • 存储溶液Preservative: 0.09% Sodium Azide
    Constituents: 0.1% BSA, Tris buffered saline
  • Concentration information loading...
  • 纯度Immunogen affinity purified
  • 克隆多克隆
  • 同种型IgG
  • 研究领域

相关产品

应用

Our Abpromise guarantee covers the use of ab72034 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/2000 - 1/10000. Detects a band of approximately 120 kDa (predicted molecular weight: 98 kDa).
IP Use at 2-5 µg/mg of lysate.

靶标

  • 功能Regulatory subunit of protein phospatase 6 (PP6). May function as a scaffolding PP6 subunit. May have an important role in maintaining immune self-tolerance.
  • 组织特异性Expressed in skeletal muscle, placenta, heart, pancreas, testis, brain, lung, liver, kidney, spleen, thymus, prostate, small intestine, colon and leukocytes.
  • 序列相似性Belongs to the SAPS family.
  • 翻译后修饰Phosphorylated upon DNA damage, probably by ATM or ATR.
  • 细胞定位Cytoplasm. Nucleus.
  • Information by UniProt
  • 数据库链接
  • 别名
    • C11orf23 antibody
    • Chromosome 11 open reading frame 23 antibody
    • KIAA1558 antibody
    • PP6R3 antibody
    • PP6R3_HUMAN antibody
    • PPP6R3 antibody
    • Protein phosphatase 6 regulatory subunit 3 antibody
    • SAP190 antibody
    • SAPL antibody
    • SAPLa antibody
    • SAPS domain family member 3 antibody
    • SAPS domain family, member 3 antibody
    • Serine/threonine-protein phosphatase 6 regulatory subunit 3 antibody
    • Sporulation induced transcript 4 associated protein SAPL antibody
    • Sporulation-induced transcript 4-associated protein SAPL antibody
    see all

Anti-SAPS3 antibody 图像

  • All lanes : Anti-SAPS3 antibody (ab72034) at 0.02 µg/ml

    Lane 1 : Whole cell lysate from Hela cells at 50 µg
    Lane 2 : Whole cell lysate from Hela cells at 15 µg
    Lane 3 : Whole cell lysate from Hela cells at 5 µg
    Lane 4 : Whole cell lysate from 293T cells at 50 µg


    Predicted band size : 98 kDa
    Observed band size : 120 kDa (why is the actual band size different from the predicted?)
  • Immunoprecipitation/ Western Blot of SAPS3.
    Lane 1: For IP: ab72034 at 3µg/mg whole cell lysate, with ab72034 at 0.04µg/ml for subsequent WB.
    Lane 2: Control IgG.

    Whole cell lysate from Hela cells at 1mg for IP, 20% of IP loaded.
    Chemiluminescence with an exposure time of 3 seconds.

Anti-SAPS3 antibody (ab72034)参考文献

ab72034 has not yet been referenced specifically in any publications.

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