概述

  • 产品名称Anti-SAPK3抗体
    参阅全部 SAPK3 一抗
  • 描述
    兔多克隆抗体to SAPK3
  • 经测试应用适用于: ELISA, WBmore details
  • 种属反应性
    与反应: Mouse, Human
  • 免疫原

    KLH conjugated synthetic peptide, selected from aa 351~367 of human SAPK3.

  • 阳性对照
    • Mouse muscle tissue lysate.

性能

应用

Our Abpromise guarantee covers the use of ab37932 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ELISA 1/1000.
WB 1/100 - 1/500. Predicted molecular weight: 42 kDa.

靶标

  • 功能Responds to activation by environmental stress and pro-inflammatory cytokines by phosphorylating downstream targets. Plays a role in myoblast differentiation and also in the down-regulation of cyclin D1 in response to hypoxia in adrenal cells suggesting MAPK12 may inhibit cell proliferation while promoting differentiation.
  • 组织特异性Highly expressed in skeletal muscle and heart.
  • 序列相似性Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.
    Contains 1 protein kinase domain.
  • 结构域The TXY motif contains the threonine and tyrosine residues whose phosphorylation activates the MAP kinases.
  • 翻译后修饰Dually phosphorylated on Thr-183 and Tyr-185, which activates the enzyme.
  • 细胞定位Cytoplasm. Mitochondrion. Mitochondrial when associated with SH3BP5.
  • Information by UniProt
  • 数据库链接
  • 别名
    • ERK 3 antibody
    • ERK 5 antibody
    • ERK 6 antibody
    • ERK-6 antibody
    • ERK3 antibody
    • ERK6 antibody
    • Extracellular signal-regulated kinase 6 antibody
    • MAP kinase 12 antibody
    • MAP kinase p38 gamma antibody
    • MAPK 12 antibody
    • Mapk12 antibody
    • Mitogen Activated Protein Kinase 12 antibody
    • Mitogen activated protein kinase 3 antibody
    • Mitogen activated protein kinase p38 gamma antibody
    • Mitogen-activated protein kinase 12 antibody
    • Mitogen-activated protein kinase p38 gamma antibody
    • MK12_HUMAN antibody
    • P38 GAMMA antibody
    • P38GAMMA antibody
    • PRKM12 antibody
    • SAPK 3 antibody
    • SAPK-3 antibody
    • SAPK3 antibody
    • Stress Activated Protein Kinase 3 antibody
    • Stress-activated protein kinase 3 antibody
    see all

Anti-SAPK3 antibody 图像

  • Anti-SAPK3 antibody (ab37932) at 1/100 dilution + mouse muscle tissue lysate

    Secondary
    HRP-anti-rabbit
    Developed using the ECL technique

    Predicted band size : 42 kDa
    Observed band size : 42 kDa

Anti-SAPK3 antibody (ab37932)参考文献

ab37932 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab37932.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"