概述

  • 产品名称Anti-SAP102抗体
    参阅全部 SAP102 一抗
  • 描述
    兔多克隆抗体to SAP102
  • 特异性We have data to indicate that this antibody may not cross react with Mouse. However, this has not been conclusively tested and expression levels may vary in certain cell lines/tissues.
  • 经测试应用适用于: IP, ICC/IF, IHC-Fr, WBmore details
  • 种属反应性
    与反应: Rat
    预测可用于: Mouse, Human
  • 免疫原

    Synthetic peptide corresponding to Rat SAP102 aa 83-100.
    Sequence:

    GPVPPKPVPGKNTPKLNG


    (Peptide available as ab5841)

性能

相关产品

应用

Our Abpromise guarantee covers the use of ab3438 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IP Use at an assay dependent concentration.
ICC/IF Use at an assay dependent concentration.
IHC-Fr Use a concentration of 10 µg/ml.
WB Use a concentration of 3 µg/ml. Can be blocked with SAP102 peptide (ab5841).

靶标

  • 功能Required for learning most likely through its role in synaptic plasticity following NMDA receptor signaling.
  • 疾病相关Defects in DLG3 are the cause of mental retardation X-linked type 90 (MRX90) [MIM:300189]. Mental retardation is characterized by significantly sub-average general intellectual functioning associated with impairments in adaptative behavior and manifested during the developmental period. Non-syndromic mental retardation patients do not manifest other clinical signs.
  • 序列相似性Belongs to the MAGUK family.
    Contains 1 guanylate kinase-like domain.
    Contains 3 PDZ (DHR) domains.
    Contains 1 SH3 domain.
  • Information by UniProt
  • 数据库链接
  • 别名
    • bA291O7.3 antibody
    • bA291O7.3 discs large Drosophila homolog 3 neuroendocrine dlg antibody
    • Discs large Drosophila homolog 3 antibody
    • Discs large homolog 3 neuroendocrine dlg Drosophila antibody
    • Discs large homolog 3 antibody
    • Discs large homolog 3 Drosophila antibody
    • Discs, large homolog 3 (Drosophila) antibody
    • Disks large homolog 3 antibody
    • DLG 3 antibody
    • Dlg3 antibody
    • DLG3_HUMAN antibody
    • KIAA1232 antibody
    • mKIAA1232 antibody
    • MRX 90 antibody
    • MRX antibody
    • MRX90 antibody
    • NE Dlg antibody
    • NEDLG antibody
    • Neuroendocrine dlg antibody
    • Neuroendocrine-DLG antibody
    • OTTHUMP00000023475 antibody
    • OTTHUMP00000023476 antibody
    • OTTHUMP00000023477 antibody
    • SAP 102 antibody
    • SAP-102 antibody
    • SAP102 antibody
    • Synapse associated protein 102 antibody
    • Synapse-associated protein 102 antibody
    • XLMR antibody
    see all

Anti-SAP102 antibody 图像

  • Western blot of SAP102 on extract from COS cells transfected with rat SAP102 using ab3438.

  • Immunohistochemistry (Frozen sections) analysis of Ammon's Horn and the dentate gyrus of the rat hippocampus labeling SAP102 with ab3438.

Anti-SAP102 antibody (ab3438)参考文献

This product has been referenced in:
  • Rastaldi MP  et al. Glomerular podocytes contain neuron-like functional synaptic vesicles. FASEB J 20:976-8 (2006). Read more (PubMed: 16585060) »
  • Jensen TP  et al. Expression of plasma membrane Ca2+ ATPase family members and associated synaptic proteins in acute and cultured organotypic hippocampal slices from rat. Brain Res Dev Brain Res 152:129-36 (2004). WB ; Rat . Read more (PubMed: 15351500) »

See all 2 Publications for this product

Product Wall

Abcam guarantees this product to work in the species/application used in this Abreview.
Application Western blot
Sample Rat Recombinant protein (HEK293)
Loading amount 50 µg
Specification HEK293
Gel Running Conditions Reduced Denaturing (7.5%)
Blocking step Milk as blocking agent for 1 hour(s) and 0 minute(s) · Concentration: 5% · Temperature: 37°C
Username

Abcam user community

Verified customer

提交于 Apr 27 2009

Abcam guarantees this product to work in the species/application used in this Abreview.
Application Western blot
Sample Rat Recombinant protein (HEK 293 cell transfected homogenates)
Loading amount 25 µg
Specification HEK 293 cell transfected homogenates
Gel Running Conditions Reduced Denaturing
Blocking step Milk as blocking agent for 1 hour(s) and 0 minute(s) · Concentration: 5% · Temperature: 37°C
Username

Abcam user community

Verified customer

提交于 Feb 13 2009

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"