概述

  • 产品名称Anti-SAFB抗体
    参阅全部 SAFB 一抗
  • 描述
    兔多克隆抗体to SAFB
  • 经测试应用适用于: WB, ICC/IFmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat, Cow
  • 免疫原

    Recombinant protein fragment corresponding to a region within amino acids 476-705 of Human SAFB (NP_002958).

  • 阳性对照
    • A431, H1299, HeLa and HepG2 cell lysates for WB; HeLa cells for ICC/IF

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • 存储溶液Preservative: 0.01% Thimerosal (merthiolate)
    Constituents: 10% Glycerol, 0.1M Tris, 0.1M Glycine, pH 7.0
  • Concentration information loading...
  • 纯度Immunogen affinity purified
  • 克隆多克隆
  • 同种型IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab97520 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/500 - 1/3000. Predicted molecular weight: 103 kDa.
ICC/IF 1/100 - 1/200.

靶标

  • 功能Binds to scaffold/matrix attachment region (S/MAR) DNA and forms a molecular assembly point to allow the formation of a 'transcriptosomal' complex (consisting of SR proteins and RNA polymerase II) coupling transcription and RNA processing (By similarity). Can function as an estrogen receptor corepressor and can also bind to the HSP27 promoter and decrease its transcription. Can inhibit cell proliferation.
  • 组织特异性Ubiquitous. Expressed at high levels in the CNS and at low levels in the liver. Expressed in a wide number of breast cancer cell lines.
  • 序列相似性Contains 1 RRM (RNA recognition motif) domain.
    Contains 1 SAP domain.
  • 细胞定位Nucleus.
  • Information by UniProt
  • 数据库链接
  • 别名
    • DKFZp779C1727 antibody
    • glutathione S transferase fusion protein antibody
    • HAP antibody
    • HET antibody
    • HSP27 ERE TATA binding protein antibody
    • HSP27 ERE-TATA-binding protein antibody
    • HSP27 estrogen response element-TATA box-binding protein antibody
    • SAF B antibody
    • SAF-B antibody
    • SAF-B1 antibody
    • SAFB 1 antibody
    • SAFB antibody
    • SAFB1 antibody
    • SAFB1_HUMAN antibody
    • Scaffold attachment factor B1 antibody
    see all

Anti-SAFB antibody 图像

  • Anti-SAFB antibody (ab97520) at 1/1000 dilution + A431 whole cell lysate at 30 µg

    Predicted band size : 103 kDa
  • ab97520, at a 1/100 dilution, staining SAFB in paraformaldehyde fixed HeLa cells by Immunofluorescence analysis.
    Lower image was merged with DNA probe.

Anti-SAFB antibody (ab97520)参考文献

ab97520 has not yet been referenced specifically in any publications.

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