概述

  • 产品名称Anti-SAFB抗体
    参阅全部 SAFB 一抗
  • 描述
    兔多克隆抗体to SAFB
  • 经测试应用适用于: IHC-Pmore details
  • 种属反应性
    与反应: Mouse, Human
    预测可用于: Rabbit, Chimpanzee, Rhesus monkey, Gorilla, Chinese Hamster, Orangutan
  • 免疫原

    Synthetic peptide, corresponding to a region within residues 875 and the C-terminus (residue 915) of human SAFB (NP_002958.2).

  • 阳性对照
    • Human breast adenocarcinoma. Mouse squamous cell carcinoma.

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • 存储溶液Preservative: 0.09% Sodium Azide
    Constituents: 0.1% BSA, Tris buffered saline
  • Concentration information loading...
  • 纯度Immunogen affinity purified
  • 克隆多克隆
  • 同种型IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab84378 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P
  • 应用说明IHC-P: 1/100 - 1/500.
    Antigen exposure is recommended.
    Antigen exposure with citrate buffer will enhance staining.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能Binds to scaffold/matrix attachment region (S/MAR) DNA and forms a molecular assembly point to allow the formation of a 'transcriptosomal' complex (consisting of SR proteins and RNA polymerase II) coupling transcription and RNA processing (By similarity). Can function as an estrogen receptor corepressor and can also bind to the HSP27 promoter and decrease its transcription. Can inhibit cell proliferation.
    • 组织特异性Ubiquitous. Expressed at high levels in the CNS and at low levels in the liver. Expressed in a wide number of breast cancer cell lines.
    • 序列相似性Contains 1 RRM (RNA recognition motif) domain.
      Contains 1 SAP domain.
    • 细胞定位Nucleus.
    • Information by UniProt
    • 数据库链接
    • 别名
      • DKFZp779C1727 antibody
      • glutathione S transferase fusion protein antibody
      • HAP antibody
      • HET antibody
      • HSP27 ERE TATA binding protein antibody
      • HSP27 ERE-TATA-binding protein antibody
      • HSP27 estrogen response element-TATA box-binding protein antibody
      • SAF B antibody
      • SAF-B antibody
      • SAF-B1 antibody
      • SAFB 1 antibody
      • SAFB antibody
      • SAFB1 antibody
      • SAFB1_HUMAN antibody
      • Scaffold attachment factor B1 antibody
      see all

    Anti-SAFB antibody 图像

    • ab84378 at 1/250, staining human SAFB in a section of human breast adenocarcinoma by immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections).
    • ab84378 at 1/250 dilution, staining SAFB in FFPE section of mouse squamous cell carcinoma, by immunohistochemistry (formalin/PFA-fixed parafin-embedded sections)

    Anti-SAFB antibody (ab84378)参考文献

    ab84378 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"