概述

描述

  • 性质Synthetic

相关产品

技术指标

Our Abpromise guarantee covers the use of ab109093 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 纯度70 - 90% by HPLC.

  • 补充说明

    - First try to dissolve a small amount of peptide in either water or buffer. The more charged residues on a peptide, the more soluble it is in aqueous solutions.
    - If the peptide doesn’t dissolve try an organic solvent e.g. DMSO, then dilute using water or buffer.
    - Consider that any solvent used must be compatible with your assay. If a peptide does not dissolve and you need to recover it, lyophilise to remove the solvent.
    - Gentle warming and sonication can effectively aid peptide solubilisation. If the solution is cloudy or has gelled the peptide may be in suspension rather than solubilised.
    - Peptides containing cysteine are easily oxidised, so should be prepared in solution just prior to use.

  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

    Information available upon request.

常规信息

  • 别名
    • Anthracycline associated resistance ARX
    • Anthracycline-associated resistance ARX
    • ARX
    • FLJ13058
    • HRIHFB2115
    • SAE 2
    • SAE2
    • SAE2_HUMAN
    • SUMO 1 activating enzyme subunit 2
    • SUMO activating enzyme subunit 2
    • SUMO-activating enzyme subunit 2
    • UBA2
    • UBA2 ubiquitin activating enzyme E1 homolog
    • Ubiquitin like 1 activating enzyme E1B
    • Ubiquitin like modifier activating enzyme 2
    • Ubiquitin-like 1-activating enzyme E1B
    • UBLE1B
    see all
  • 功能The heterodimer acts as a E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2.
  • 通路Protein modification; protein sumoylation.
  • 序列相似性Belongs to the ubiquitin-activating E1 family.
  • 细胞定位Nucleus.
  • Information by UniProt

SAE2 / UBA2 peptide (ab109093)参考文献

ab109093 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab109093.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"