概述

  • 产品名称Anti-SAE1抗体
    参阅全部 SAE1 一抗
  • 描述
    小鼠单克隆抗体to SAE1
  • 经测试应用适用于: WB, IHC-Pmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Recombinant full length protein, corresponding to amino acids 1-347 of Human SAE1

性能

应用

Our Abpromise guarantee covers the use of ab56957 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB
IHC-P
  • 应用说明WB: Use at a concentration of 1-5 µg/ml.
    IHC-P: Use at a concentration of 3 µg/ml.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能The heterodimer acts as a E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2.
    • 组织特异性Expression level increases during S phase and drops in G2 phase (at protein level).
    • 通路Protein modification; protein sumoylation.
    • 序列相似性Belongs to the ubiquitin-activating E1 family.
    • 翻译后修饰Phosphorylated upon DNA damage, probably by ATM or ATR.
    • 细胞定位Nucleus.
    • Information by UniProt
    • 数据库链接
    • 别名
      • Activator of SUMO1 antibody
      • AOS1 antibody
      • HSPC140 antibody
      • Sae1 antibody
      • SAE1_HUMAN antibody
      • Sentrin/SUMO activating protein AOS1 antibody
      • SUA1 antibody
      • SUMO 1 activating enzyme E1 N subunit antibody
      • SUMO 1 activating enzyme subunit 1 antibody
      • SUMO-activating enzyme subunit 1 antibody
      • Ubiquitin like protein SUMO1 activating enzyme antibody
      • Ubiquitin-like 1-activating enzyme E1A antibody
      • UBL E1A antibody
      • UBLE1A antibody
      see all

    Anti-SAE1 antibody 图像



    • Predicted band size : 38 kDa
      SAE1 antibody (ab56957) at 1ug/lane + HeLa cell lysate at 25ug/lane.
    • SAE1 antibody (ab56957) used in immunohistochemistry at 3ug/ml on formalin fixed and paraffin embedded human adrenal gland.

    Anti-SAE1 antibody (ab56957)参考文献

    This product has been referenced in:

    See all 2 Publications for this product

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