RabMAb

Anti-S100 Calcium Binding Protein A13抗体[EPR4510] (ab109252)

概述

  • 产品名称Anti-S100 Calcium Binding Protein A13抗体[EPR4510]
    参阅全部 S100 Calcium Binding Protein A13 一抗
  • 描述
    兔单克隆抗体[EPR4510] to S100 Calcium Binding Protein A13
  • 经测试应用适用于: WB, IP, IHC-P, ICC, Flow Cytmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    A synthetic peptide corresponding to residues in Human S100 Calcium Binding Protein A13.

  • 阳性对照
    • Human thyroid and testis, HUVEC and ECV304 cell lysates; Human brain and muscle tissues.
  • 常规说明

    This product is a recombinant rabbit monoclonal antibody.

    Produced using Abcam’s RabMAb® technology. RabMAb® technology is covered by the following U.S. Patents, No. 5,675,063 and/or 7,429,487.

    Mouse, Rat: We have preliminary internal testing data to indicate this antibody may not react with these species. Please contact us for more information.

性能

应用

Our Abpromise guarantee covers the use of ab109252 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/1000 - 1/10000. Predicted molecular weight: 11 kDa.
IP 1/10 - 1/100.
IHC-P 1/250 - 1/500. Perform heat mediated antigen retrieval before commencing with IHC staining protocol.

Use of a HRP/AP polymerized antibody recommended.

ICC 1/100 - 1/250.
Flow Cyt 1/10 - 1/100.

ab172730 - Rabbit monoclonal IgG, is suitable for use as an isotype control with this antibody.

靶标

  • 功能Plays a role in the export of proteins that lack a signal peptide and are secreted by an alternative pathway. Binds two calcium ions per subunit. Binds one copper ion. Binding of one copper ion does not interfere with calcium binding. Required for the copper-dependent stress-induced export of IL1A and FGF1. The calcium-free protein binds to lipid vesicles containing phosphatidylserine, but not to vesicles containing phosphatidylcholine.
  • 组织特异性Expressed in heart and skeletal muscle.
  • 序列相似性Belongs to the S-100 family.
    Contains 2 EF-hand domains.
  • 细胞定位Cytoplasm. Secreted. Secretion is mediated by exposure to stress and requires copper ions.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Protein S100 A13 antibody
    • Protein S100-A13 antibody
    • S100 calcium binding protein A13 antibody
    • S100 calcium-binding protein A13 antibody
    • S100a13 antibody
    • S10AD_HUMAN antibody
    see all

Anti-S100 Calcium Binding Protein A13 antibody [EPR4510] 图像

  • All lanes : Anti-S100 Calcium Binding Protein A13 antibody [EPR4510] (ab109252) at 1/1000 dilution

    Lane 1 : Human thyroid tissue lysate
    Lane 2 : Human testis tissue lysate
    Lane 3 : HUVEC lysate
    Lane 4 : ECV304 lysate

    Lysates/proteins at 10 µg per lane.


    Predicted band size : 11 kDa
  • ab109252, at a 1/250 dilution, staining S100 Calcium Binding Protein A13 in Human brain, by Immunohistochemistry, Paraffin-embedded tissue.
  • ab109252, at a 1/250 dilution, staining S100 Calcium Binding Protein A13 in Human muscle, by Immunohistochemistry, Paraffin-embedded tissue.

Anti-S100 Calcium Binding Protein A13 antibody [EPR4510] (ab109252)参考文献

ab109252 has not yet been referenced specifically in any publications.

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