概述

  • 产品名称Anti-S100 beta抗体
    参阅全部 S100 beta 一抗
  • 描述
    兔多克隆抗体to S100 beta
  • 特异性Does not cross react with other calcium binding proteins including calbindin, calretinin or parvalbumins.
  • 经测试应用适用于: IPmore details
    不适用于: IHC-Fr
  • 种属反应性
    与反应: Mouse, Rat, Human
  • 免疫原

    Full length native protein homodimer (purified) (Human) (Peptide available as ab30380.)

  • 阳性对照
    • Rat brain tissue lysate.

性能

相关产品

应用

Our Abpromise guarantee covers the use of ab14688 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IP 1/250.
  • 应用说明Is unsuitable for IHC-Fr.
  • 靶标

    • 功能Weakly binds calcium but binds zinc very tightly-distinct binding sites with different affinities exist for both ions on each monomer. Physiological concentrations of potassium ion antagonize the binding of both divalent cations, especially affecting high-affinity calcium-binding sites. Binds to and initiates the activation of STK38 by releasing autoinhibitory intramolecular interactions within the kinase. Interaction with AGER after myocardial infarction may play a role in myocyte apoptosis by activating ERK1/2 and p53/TP53 signaling.
    • 组织特异性Although predominant among the water-soluble brain proteins, S100 is also found in a variety of other tissues.
    • 序列相似性Belongs to the S-101 family.
      Contains 2 EF-hand domains.
    • 细胞定位Cytoplasm. Nucleus.
    • Information by UniProt
    • 数据库链接
    • 别名
      • NEF antibody
      • Protein S100 B antibody
      • Protein S100-B antibody
      • S 100 calcium binding protein beta chain antibody
      • S 100 protein beta chain antibody
      • S-100 protein beta chain antibody
      • S-100 protein subunit beta antibody
      • S100 antibody
      • S100 calcium binding protein beta (neural) antibody
      • S100 calcium-binding protein B antibody
      • S100 protein beta chain antibody
      • S100B antibody
      • S100B_HUMAN antibody
      • S100beta antibody
      see all

    Anti-S100 beta antibody (ab14688)参考文献

    This product has been referenced in:

    See all 3 Publications for this product

    Product Wall

    Thank you for contacting us.  Unfortunately, I was unable to locate any amino acid sequences for Tilapia S100, S100 beta, or Dopamine D2 Receptor with which to compare the immunogen sequences for these antibodies.  For this reason, we have no informati...

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    Abcam has not validated the combination of species/application used in this Abreview.
    Application Immunohistochemistry (Frozen sections)
    Sample Rat Tissue sections (Adult rat brain)
    Specification Adult rat brain
    Fixative Paraformaldehyde
    Permeabilization No
    Username

    Dr. Sophie Pezet

    Verified customer

    提交于 Aug 29 2007

    I am sorry to hear that you have been having difficulties with this antibody. I have read your technical questionnaire and I have a few comments. S100 beta is a very small protein. It can be difficult to detect small proteins by using western blott...

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"