Anti-S100抗体[S100 217] (ab115968)

概述

  • 产品名称Anti-S100抗体[S100 217]
    参阅全部 S100 一抗
  • 描述
    小鼠单克隆抗体[S100 217] to S100
  • 经测试应用适用于: IHC-P, IHC-Fr, ICCmore details
  • 种属反应性
    与反应: Mouse, Rat, Cow, Human, Monkey
  • 免疫原

    Purified Cow S100 protein.

  • 阳性对照
    • Human Melanoma or schwannoma tissues.
  • 常规说明


    ab115968 stains schwannoma, ependymomas, astrogliomas, almost all benign and malignant melanoma and their metastases. ab115968 is made with the 22 kDa S100 protein and the antibody reacts with alpha and beta S100 protein.

性能

应用

Our Abpromise guarantee covers the use of ab115968 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P 1/50 - 1/100.
IHC-Fr 1/50 - 1/100.
ICC Use at an assay dependent concentration.

靶标

  • 功能Weakly binds calcium but binds zinc very tightly-distinct binding sites with different affinities exist for both ions on each monomer. Physiological concentrations of potassium ion antagonize the binding of both divalent cations, especially affecting high-affinity calcium-binding sites.
  • 组织特异性Highly prevalent in heart. Also found in lesser quantities in skeletal muscle and brain.
  • 序列相似性Belongs to the S-100 family.
    Contains 2 EF-hand domains.
  • 细胞定位Cytoplasm.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Bpb antibody
    • NEF antibody
    • Protein S100-A1 antibody
    • S-100 protein alpha chain antibody
    • S-100 protein subunit alpha antibody
    • S100 alpha antibody
    • S100 beta antibody
    • S100 calcium binding protein A1 antibody
    • S100 calcium binding protein B antibody
    • S100 calcium-binding protein A1 antibody
    • S100 protein alpha polypeptide antibody
    • S100A antibody
    • s100a1 antibody
    • S100B antibody
    • S100beta antibody
    • S10A1_HUMAN antibody
    see all

Anti-S100 antibody [S100 217] (ab115968)参考文献

ab115968 has not yet been referenced specifically in any publications.

Product Wall

Thank you for your inquiry. Yes, both ab7852 and ab115968 react with the alpha and beta subunits of S-100 protein.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"