Anti-Ryanodine Receptor 3抗体- Carboxyterminal end (ab56000)

概述

  • 产品名称Anti-Ryanodine Receptor 3抗体- Carboxyterminal end
  • 描述
    兔多克隆抗体to Ryanodine Receptor 3 - Carboxyterminal end
  • 经测试应用适用于: WB, ELISAmore details
  • 种属反应性
    与反应: Recombinant Fragment
    预测可用于: Human
  • 免疫原

    A synthetic peptide corresponding to C-terminal residues of human Ryanodine Receptor 3

性能

应用

Our Abpromise guarantee covers the use of ab56000 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 552 kDa. for 2 hours. This antibody has been tested in Western blot against the recombinant peptide used as an immunogen. We have no data on detection of endogenous protein.
ELISA Use at an assay dependent dilution.

靶标

  • 功能Communication between transverse-tubules and sarcoplasmic reticulum. Contraction of skeletal muscle is triggered by release of calcium ions from SR following depolarization of T-tubules.
  • 组织特异性Brain, skeletal muscle, placenta and possibly liver and kidney. In brain, highest levels are found in the cerebellum, hippocampus, caudate nucleus and amygdala, with lower levels in the corpus callosum, substantia nigra and thalamus.
  • 序列相似性Belongs to the ryanodine receptor (TC 1.A.3.1) family. RYR3 subfamily.
    Contains 3 B30.2/SPRY domains.
    Contains 1 EF-hand domain.
    Contains 5 MIR domains.
  • 细胞定位Membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Brain ryanodine receptor calcium release channel antibody
    • Brain ryanodine receptor-calcium release channel antibody
    • Brain type ryanodine receptor antibody
    • Brain-type ryanodine receptor antibody
    • HBRR antibody
    • Ryanodine receptor 3 antibody
    • RYR 3 antibody
    • RYR-3 antibody
    • RyR3 antibody
    • RYR3_HUMAN antibody
    see all

Anti-Ryanodine Receptor 3 antibody - Carboxyterminal end (ab56000)参考文献

This product has been referenced in:
  • Nensa FM  et al. Amyloid beta a4 precursor protein-binding family B member 1 (FE65) interactomics revealed synaptic vesicle glycoprotein 2A (SV2A) and sarcoplasmic/endoplasmic reticulum calcium ATPase 2 (SERCA2) as new binding proteins in the human brain. Mol Cell Proteomics 13:475-88 (2014). Read more (PubMed: 24284412) »

See 1 Publication for this product

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