Anti-RYR-3抗体(ab56000)
Key features and details
- Rabbit polyclonal to RYR-3
- Suitable for: ELISA, WB
- Reacts with: Recombinant fragment
- Isotype: IgG
概述
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产品名称
Anti-RYR-3抗体 -
描述
兔多克隆抗体to RYR-3 -
宿主
Rabbit -
经测试应用
适用于: ELISA, WBmore details -
种属反应性
与反应: Recombinant fragment
预测可用于: Human -
免疫原
Synthetic peptide corresponding to Human RYR-3 (C terminal).
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
存储溶液
pH: 7.2
Preservative: 0.01% Sodium azide
Constituents: 50% Glycerol (glycerin, glycerine), PBS -
Concentration information loading...
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纯度
Immunogen affinity purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab56000于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
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ELISA |
Use at an assay dependent concentration.
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WB |
Use at an assay dependent concentration. Predicted molecular weight: 552 kDa.
for 2 hours. This antibody has been tested in Western blot against the recombinant peptide used as an immunogen. We have no data on detection of endogenous protein. |
说明 |
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ELISA
Use at an assay dependent concentration. |
WB
Use at an assay dependent concentration. Predicted molecular weight: 552 kDa. for 2 hours. This antibody has been tested in Western blot against the recombinant peptide used as an immunogen. We have no data on detection of endogenous protein. |
靶标
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功能
Communication between transverse-tubules and sarcoplasmic reticulum. Contraction of skeletal muscle is triggered by release of calcium ions from SR following depolarization of T-tubules. -
组织特异性
Brain, skeletal muscle, placenta and possibly liver and kidney. In brain, highest levels are found in the cerebellum, hippocampus, caudate nucleus and amygdala, with lower levels in the corpus callosum, substantia nigra and thalamus. -
序列相似性
Belongs to the ryanodine receptor (TC 1.A.3.1) family. RYR3 subfamily.
Contains 3 B30.2/SPRY domains.
Contains 1 EF-hand domain.
Contains 5 MIR domains. -
细胞定位
Membrane. - Information by UniProt
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数据库链接
- Entrez Gene: 6263 Human
- Omim: 180903 Human
- SwissProt: Q15413 Human
- Unigene: 709373 Human
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别名
- Brain ryanodine receptor calcium release channel antibody
- Brain ryanodine receptor-calcium release channel antibody
- Brain type ryanodine receptor antibody
see all
数据表及文件
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SDS download
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Datasheet download
文献 (1)
ab56000 被引用在 1 文献中.
- Nensa FM et al. Amyloid beta a4 precursor protein-binding family B member 1 (FE65) interactomics revealed synaptic vesicle glycoprotein 2A (SV2A) and sarcoplasmic/endoplasmic reticulum calcium ATPase 2 (SERCA2) as new binding proteins in the human brain. Mol Cell Proteomics 13:475-88 (2014). PubMed: 24284412