概述

描述

  • 性质
    Synthetic

相关产品

技术指标

Our Abpromise guarantee covers the use of ab117773 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    Blocking - Blocking peptide for Anti-RWDD3 antibody (ab91555)

  • 形式
    Liquid

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

    Preservative: 0.02% Sodium azide
    Constituents: PBS, 0.1% BSA

常规信息

  • 别名
    • DKFZp566K023
    • RSUME
    • RWD containing sumoylation enhancer
    • RWD domain containing 3
    • RWD domain containing protein
    • RWD domain containing protein 3
    • RWD domain-containing protein 3
    • RWD-containing sumoylation enhancer
    • rwdd3
    • RWDD3_HUMAN
    see all
  • 功能
    Enhances the sumoylation of a number of proteins including HIF1A, PIAS and I-kappa-B, through direct interaction with UBC9. Has no effect on ubiquitination.
  • 组织特异性
    Expressed in a wide number of tissues with highest expression in cerebellum, pituitary, heart, kidney, liver, stomach, pancreas, prostate and spleen. Low levels in thalamus, spinal cord, esophagus, thymus, lung and peripheral blood leukocytes.
  • 序列相似性
    Contains 1 RWD domain.
  • 结构域
    The RWD domain is required for the sumoylation enhancement activity.
  • 细胞定位
    Nucleus. Cytoplasm. Colocalizes with UBC9/UBE2I in nuclear spots.
  • Information by UniProt

文献

ab117773 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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