Anti-Russells Viper Venom抗体(ab67822)

概述

  • 产品名称Anti-Russells Viper Venom抗体
  • 描述
    鸭多克隆抗体to Russells Viper Venom
  • 特异性This antibody specifically recognized russell’s viper venom in western blot analysis; it also partially recognized venom of N. naja atra (45kDa), D. acutus (45 and 105kDa), T.stejnegeri (60 and 105kDa), and T. mucrosquamatus (45 and 105kDa).
  • 经测试应用适用于: ELISA, WBmore details
  • 种属反应性
    与反应: Snake
  • 免疫原

    Snake Venom of Daboia russelli

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • 存储溶液Preservative: 0.005% Thimerosal (merthiolate)
    Constituents: 0.14M Sodium chloride, 10mM PBS, pH 7.0
  • Concentration information loading...
  • 纯度IgY fraction
  • 纯化说明This antibody was purified from egg yolk. Purity was determined by SDS PAGE. IgY(delta Fc) constitutes ~80% of total protein, and the total immunoglobulin IgY+IgY(delta Fc) constitutes ~90% of total protein.
  • 克隆多克隆
  • 同种型IgY
  • 研究领域

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应用

Our Abpromise guarantee covers the use of ab67822 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ELISA
WB
  • 应用说明ELISA titer : 1/10000
    ELISA titer is defined as the dilution of antibody (1mg/ml) sufficient to give a change in absorbance of 1.0 at 450nm.

    WB: Use at an assay dependent dilution.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 相关性Daboia russelli (Russell's viper) is a venomous snake found throughout the Indian subcontinent, much of Southeast Asia, southern China and Taiwan. The venom of this snake is so effective at inducing thrombosis, it has been incorporated into an in vitro diagnostic test for blood clotting that is widely used in hospital laboratories. This test is often referred to as Dilute Russell's viper venom time (dRVVT). The coagulant in the venom directly activates factor X, which turns prothrombin into thrombin in the presence of factor V and phospholipid. The venom is diluted to give a clotting time of 23 to 27 seconds and the phospholipid is reduced to make the test extremely sensitive to phospholipid. The dRVVT test is more sensitive than the aPTT test for the detection of lupus anticoagulant (an autoimmune disorder), because it is not influenced by deficiencies in clotting factors VIII, IX or XI.
    • 细胞定位Secreted
    • 数据库链接
    • 别名
      • Indian Russell's viper venom antibody

    Anti-Russells Viper Venom antibody (ab67822)参考文献

    ab67822 has not yet been referenced specifically in any publications.

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