Morita K et al.RUNX transcription factors potentially control E-selectin expression in the bone marrow vascular niche in mice.Blood Adv 2:509-515 (2018).
Zheng J et al.DNA methylation affects metastasis of renal cancer and is associated with TGF-ß/RUNX3 inhibition.Cancer Cell Int 18:56 (2018).
Morita K et al.Paradoxical enhancement of leukemogenesis in acute myeloid leukemia with moderately attenuated RUNX1 expressions.Blood Adv 1:1440-1451 (2017).
Morita K et al.Genetic regulation of the RUNX transcription factor family has antitumor effects.J Clin Invest 127:2815-2828 (2017).
Lai CB & Mager DL Role of Runt-related Transcription Factor 3 (RUNX3) in Transcription Regulation of Natural Cytotoxicity Receptor 1 (NCR1/NKp46), an Activating Natural Killer (NK) Cell Receptor.J Biol Chem 287:7324-34 (2012).
WB, ChIP, EMSA
Ciavatta DJ et al.Epigenetic basis for aberrant upregulation of autoantigen genes in humans with ANCA vasculitis.J Clin Invest 120:3209-19 (2010).
Weersma RK et al.Runt-related transcription factor 3 is associated with ulcerative colitis and shows epistasis with solute carrier family 22, members 4 and 5.Inflamm Bowel Dis 14:1615-22 (2008).
Chen PC et al.Novel roles for MLH3 deficiency and TLE6-like amplification in DNA mismatch repair-deficient gastrointestinal tumorigenesis and progression.PLoS Genet 4:e1000092 (2008).
Cheng CK et al.Transcriptional repression of the RUNX3/AML2 gene by the t(8;21) and inv(16) fusion proteins in acute myeloid leukemia.Blood 112:3391-402 (2008).