概述

  • 产品名称Anti-RUFY1抗体
    参阅全部 RUFY1 一抗
  • 描述
    兔多克隆抗体to RUFY1
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat
  • 免疫原

    Recombinant fragment corresponding to a region within amino acids 293-464 of Human RUFY1 (AAH32571).

  • 阳性对照
    • U87-MG whole cell lysate; IMR32 and MCF7 cell lysates

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • 存储溶液Preservative: 0.01% Thimerosal (merthiolate)
    Constituents: 20% Glycerol, 0.1M Tris, 0.1M Glycine, pH 7.0
  • Concentration information loading...
  • 纯度Immunogen affinity purified
  • 克隆多克隆
  • 同种型IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab101519 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/500 - 1/3000. Predicted molecular weight: Isoform 1, 80 ; Isoform 2, 69 kDa.

靶标

  • 功能Binds phospholipid vesicles containing phosphatidylinositol 3-phosphate and participates in early endosomal trafficking.
  • 组织特异性Broadly expressed, with highest levels in lung, testis, kidney and brain.
  • 序列相似性Contains 1 FYVE-type zinc finger.
    Contains 1 RUN domain.
  • 结构域The FYVE-type zinc finger domain mediates interactions with phosphatidylinositol 3-phosphate in membranes of early endosomes and penetrates bilayers. The FYVE domain insertion into PtdIns(3)P-enriched membranes is substantially increased in acidic conditions.
  • 翻译后修饰Phosphorylation on Tyr-389 and/or Tyr-400 is required for interaction with BMX and endosomal targeting.
    Phosphorylated upon DNA damage, probably by ATM or ATR.
  • 细胞定位Cytoplasm. Early endosome membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • 3000002E04Rik antibody
    • FLJ22251 antibody
    • FYVE finger protein EIP1 antibody
    • FYVE-finger protein EIP1 antibody
    • La binding protein 1 antibody
    • La-binding protein 1 antibody
    • OTTHUMP00000161521 antibody
    • Rab4 interacting protein antibody
    • Rab4-interacting protein antibody
    • RABIP4 antibody
    • RUFY1 antibody
    • RUFY1_HUMAN antibody
    • RUN and FYVE domain containing 1 antibody
    • RUN and FYVE domain-containing protein 1 antibody
    • RUN and FYVE domains containing protein 1 antibody
    • ZFYVE12 antibody
    • Zinc finger FYVE domain containing protein 12 antibody
    • Zinc finger FYVE domain-containing protein 12 antibody
    see all

Anti-RUFY1 antibody 图像

  • Anti-RUFY1 antibody (ab101519) at 1/1000 dilution + U87-MG whole cell lysate at 30 µg

    Predicted band size : Isoform 1, 80 ; Isoform 2, 69 kDa

Anti-RUFY1 antibody (ab101519)参考文献

ab101519 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab101519.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"