Anti-Rubella virus E1抗体[Ru6] (ab82464)

概述

  • 产品名称Anti-Rubella virus E1抗体[Ru6]
  • 描述
    小鼠单克隆抗体[Ru6] to Rubella virus E1
  • 经测试应用适用于: WB, ELISAmore details
  • 种属反应性
    Reacts with Rubella Virus
  • 免疫原

    Purified Rubella virus, strain HPV72.

性能

应用

Our Abpromise guarantee covers the use of ab82464 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use at an assay dependent dilution. Predicted molecular weight: 52 kDa.
ELISA Use at an assay dependent dilution.

靶标

  • 相关性Rubella virus is the only member of the Rubrivirus genus of the Togavirus family. Unlike most Togaviruses it is NOT arthropod borne, but is acquired via the respiratory route. It is an enveloped (toga=cloak), non-segmented, positive sense, RNA virus and replicates in the cytoplasm. It consists of 3 structural proteins; E1,E2 membrane bound glycoproteins, and C capsid protein. E1 envelope glycoprotein is a class II viral fusion protein. Fusion activity is inactive as long as E1 is bound to E2 in mature virion. After virus attachment to target cell and endocytosis, acidification of the endosome induces dissociation of E1/E2 heterodimer and trimerization of the E1 subunits. This E1 homotrimer is fusion active, and promotes release of viral nucleocapsid in the cytoplasm after cell and viral membrane fusion. The E1 cytoplasmic tail modulates virus release, and the tyrosines residues are critical for this function.
  • 别名
    • E1 antibody
    • E1 envelope glycoprotein antibody
    • Glycoprotein E1 antibody
    • Spike glycoprotein E1 antibody

Anti-Rubella virus E1 antibody [Ru6] (ab82464)参考文献

ab82464 has not yet been referenced specifically in any publications.

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Thank you very much for contacting us with your question, and for your patience while I've been in touch with the lab about the epitope of this antibody.
Unfortunately we have not determined the epitope of ab82464. We only know that it binds to t...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"