概述

  • 产品名称Anti-RSG1抗体
    参阅全部 RSG1 一抗
  • 描述
    兔多克隆抗体to RSG1
  • 经测试应用适用于: IHC-P, WB, ICC/IFmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    KFDQYMHTDV PERDLTAFRQ AWELPLLRVK SVPGRRLADG RTLDGRAGLA DVAHILNGLA EQLWHQDQVA AGLLPNPPES APE, corresponding to amino acids 176-258 of Human RSG1 (Q9BU20).

  • 阳性对照
    • Human liver tissue

性能

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应用

Our Abpromise guarantee covers the use of ab121990 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P 1/20 - 1/50. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
WB Use at an assay dependent concentration.
ICC/IF Use a concentration of 1 - 4 µg/ml.

Recommend PFA Fixation and Triton X-100 treatment

靶标

  • 功能Potential effector of the planar cell polarity signaling pathway. Plays a role in targeted membrane trafficking most probably at the level of vesicle fusion with membranes. Involved in cilium biogenesis by regulating the transport of cargo proteins to the basal body and to the apical tips of cilia. More generally involved in exocytosis in secretory cells.
  • 序列相似性Belongs to the small GTPase superfamily. Rab family.
  • 细胞定位Cytoplasm > cytoskeleton > cilium basal body.
  • Information by UniProt
  • 数据库链接
  • 别名
    • C1orf89 antibody
    • Miro domain containing protein C1orf89 antibody
    • Rem/Rab Similar GTPase 1 antibody
    • REM2- and Rab-like small GTPase 1 antibody
    • RP4-733M16.4 antibody
    • Rsg1 antibody
    • RSG1_HUMAN antibody
    see all

Anti-RSG1 antibody 图像

  • Immunofluorescent staining of Human cell line A-431 shows positivity in nuclei but not nucleoli. Recommended concentration of ab121990 1-4 µg/ml. Cells treated with PFA/Triton X-100.
  • ab121990, at 1/40 dilution, staining RSG1 in Paraffin-embedded Human liver tissue by Immunohistochemistry.
  • Lane 1: Marker [kDa] 250; 130; 95; 72; 55; 36; 28; 17; 10
    Lane 2: Negative control (vector only transfected HEK293T lysate)
    Lane 3: Over-expression Lysate (Co-expressed with a C-terminal myc-DDK tag (~3.1 kDa) in mammalian HEK293T cells. Lane 1: Marker [kDa] 250; 130; 95; 72; 55; 36; 28; 17; 10
    Lane 2: Negative control (vector only transfected HEK293T lysate)
    Lane 3: Over-expression Lysate (Co-expressed with a C-terminal myc-DDK tag (~3.1 kDa) in mammalian HEK293T cells.

Anti-RSG1 antibody (ab121990)参考文献

ab121990 has not yet been referenced specifically in any publications.

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