概述

  • 产品名称
    Anti-RSF1抗体[EPR3749(2)]
    参阅全部 RSF1 一抗
  • 描述
    兔单克隆抗体[EPR3749(2)] to RSF1
  • 经测试应用
    适用于: WB, IHC-P, ICCmore details
    不适用于: Flow Cyt or IP
  • 种属反应性
    与反应: Human
  • 免疫原

    A synthetic peptide corresponding to residues in Human RSF1.

  • 阳性对照
    • Jurkat, 293T and HeLa cell lysates; Human colon, endometrial adenocarcinoma and tonsil tissues.
  • 常规说明

    This product is a recombinant rabbit monoclonal antibody.

    Mouse, Rat: We have preliminary internal testing data to indicate this antibody may not react with these species. Please contact us for more information.

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents

性能

相关产品

应用

Our Abpromise guarantee covers the use of ab109002 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/1000 - 1/10000. Predicted molecular weight: 164 kDa.
IHC-P 1/250 - 1/500. Antigen retrieval is recommended.
ICC 1/500 - 1/1000.
  • 应用说明
    Is unsuitable for Flow Cyt or IP.
  • 靶标

    • 相关性
      RSF1 is involved in transcription repression when recruited to DNA via the DNA binding of GAL4. It is also involved in chromatin remodeling and spacing when associated with SNF2H and transcription coactivation when associated with hepatitis B virus X protein (HBX). The RSF1 gene is localized to the long arm of human chromosome 11 between q13.4 and q14.1. This region is amplified and rearranged in many tumors, indicating that it plays a role in tumorigenesis similar to that of other PHD-containing proteins.
    • 细胞定位
      Nuclear
    • 数据库链接
    • 别名
      • HBV pX associated protein 8 antibody
      • Hepatitis B virus x associated protein antibody
      • HXBAP antibody
      • p325 antibody
      • p325 subunit of RSF chromatin remodeling complex antibody
      • remodeling and spacing factor 1 antibody
      • RSF 1 antibody
      • XAP8 antibody
      see all

    图片

    • All lanes : Anti-RSF1 antibody [EPR3749(2)] (ab109002) at 1/1000 dilution

      Lane 1 : Jurkat cell lysate
      Lane 2 : 293T cell lysate
      Lane 3 : HeLa cell lysate

      Lysates/proteins at 10 µg per lane.


      Predicted band size : 164 kDa
    • ab109002 at 1/250 dilution, staining RSF1 in Human colon by Immunohistochemistry, Paraffin-embedded tissue.
    • ab109002 at 1/250 dilution, staining RSF1 in Human endometrial adenocarcinoma by Immunohistochemistry, Paraffin-embedded tissue.
    • ab109002 at 1/250 dilution, staining RSF1 in Human tonsil by Immunohistochemistry, Paraffin-embedded tissue.

    文献

    This product has been referenced in:
    • Lee HS  et al. The chromatin remodeller RSF1 is essential for PLK1 deposition and function at mitotic kinetochores. Nat Commun 6:7904 (2015). ICC . Read more (PubMed: 26259146) »
    • Ren J  et al. Overexpression of Rsf-1 correlates with pathological type, p53 status and survival in primary breast cancer. Int J Clin Exp Pathol 7:5595-608 (2014). IHC ; Human . Read more (PubMed: 25337201) »

    See all 2 Publications for this product

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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