概述

  • 产品名称
  • 描述
    兔多克隆抗体to RRM2
  • 经测试应用
    适用于: WBmore details
  • 种属反应性
    与反应: Human
    预测可用于: Rat, Horse, Guinea pig, Cow, Cat, Dog, Pig
  • 免疫原

    Synthetic peptide corresponding to a region within the N terminal amino acids 36-85 (ALSGTRVLAS KTARRIFQEP TEPKTKAAAP GVEDEPLLRE NPRRFVIFPI) of Human RRM2 (NP_001025).

  • 阳性对照
    • Human fetal muscle lysate.

性能

  • 形式
    Liquid
  • 存放说明
    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
  • 存储溶液
    Preservative: None
    Constituents: 2% Sucrose, PBS
  • Concentration information loading...
  • 纯度
    Immunogen affinity purified
  • 克隆
    多克隆
  • 同种型
    IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab87227 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 45 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

靶标

  • 功能
    Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. Inhibits Wnt signaling.
  • 通路
    Genetic information processing; DNA replication.
  • 序列相似性
    Belongs to the ribonucleoside diphosphate reductase small chain family.
  • 翻译后修饰
    Phosphorylation on Ser-20 relieves the inhibitory effect on Wnt signaling.
  • 细胞定位
    Cytoplasm.
  • Information by UniProt
  • 数据库链接
  • 别名
    • cb111 antibody
    • chunp6884 antibody
    • etID309896.20 antibody
    • R2 antibody
    • reductase M2 polypeptide variant 1 antibody
    • reductase M2 polypeptide variant 2 antibody
    • reductase M2 polypeptide variant 3a antibody
    • reductase M2 polypeptide variant 3b antibody
    • reductase M2 polypeptide variant 3c antibody
    • reductase M2 polypeptide variant 3d antibody
    • Ribonucleoside-diphosphate reductase subunit M2 antibody
    • Ribonucleotide reductase M2 antibody
    • Ribonucleotide reductase M2 polypeptide antibody
    • Ribonucleotide reductase M2 subunit antibody
    • ribonucleotide reductase protein r2 class I antibody
    • Ribonucleotide reductase regulatory subunit M2 antibody
    • Ribonucleotide reductase small chain antibody
    • Ribonucleotide reductase small subunit antibody
    • Ribonucleotide reductase, R2 subunit antibody
    • RIR2_HUMAN antibody
    • RR2 antibody
    • RR2M antibody
    • RRM2 antibody
    see all

Anti-RRM2 antibody 图像

  • Anti-RRM2 antibody (ab87227) at 1 µg/ml (in 5% skim milk / PBS buffer) + human fetal muscle lysate at 10 µg

    Secondary
    HRP conjugated anti-Rabbit IgG at 1/50000 dilution

    Predicted band size : 45 kDa
    Observed band size : 40 kDa (why is the actual band size different from the predicted?)
    Additional bands at : 38 kDa. We are unsure as to the identity of these extra bands.

实验方案

Anti-RRM2 antibody (ab87227)参考文献

ab87227 has not yet been referenced specifically in any publications.

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