Anti-RRBP1抗体(ab95983)
Key features and details
- Rabbit polyclonal to RRBP1
- Suitable for: WB, IHC-P, ICC/IF
- Reacts with: Mouse, Human
- Isotype: IgG
概述
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产品名称
Anti-RRBP1抗体
参阅全部 RRBP1 一抗 -
描述
兔多克隆抗体to RRBP1 -
宿主
Rabbit -
经测试应用
适用于: WB, IHC-P, ICC/IFmore details -
种属反应性
与反应: Mouse, Human -
免疫原
Recombinant fragment. This information is proprietary to Abcam and/or its suppliers.
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阳性对照
- WB: NIH-3T3 whole cell lysate. IHC-P: OVCAR3 cell ICC/IF: HeLa cell
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles. -
存储溶液
pH: 7.00
Preservative: 0.01% Thimerosal (merthiolate)
Constituents: 59.99% PBS, 40% Glycerol (glycerin, glycerine) -
Concentration information loading...
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纯度
Immunogen affinity purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
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Positive Controls
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab95983于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
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WB |
1/500 - 1/3000. Predicted molecular weight: 109 kDa.
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IHC-P |
1/100 - 1/1000.
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ICC/IF |
1/100 - 1/1000.
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说明 |
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WB
1/500 - 1/3000. Predicted molecular weight: 109 kDa. |
IHC-P
1/100 - 1/1000. |
ICC/IF
1/100 - 1/1000. |
靶标
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功能
Acts as a ribosome receptor and mediates interaction between the ribosome and the endoplasmic reticulum membrane. -
细胞定位
Endoplasmic reticulum membrane. - Information by UniProt
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数据库链接
- Entrez Gene: 6238 Human
- Entrez Gene: 81910 Mouse
- Omim: 601418 Human
- SwissProt: Q9P2E9 Human
- SwissProt: Q99PL5 Mouse
- Unigene: 472213 Human
- Unigene: 13705 Mouse
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别名
- 180 kDa ribosome receptor homolog antibody
- DKFZp586A1420 antibody
- ES/130 antibody
see all
图片
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Immunofluorescence analysis of paraformaldehyde fixed HeLa, using ab95983 at 1/200 dilution. Lower image merged with DNA probe.
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Immunohistochemical analysis of paraffin embedded OVCAR3, using ab95983 at 1/500 dilution.
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Anti-RRBP1 antibody (ab95983) at 1/1000 dilution + NIH 3T3 whole cell lysate at 30 µg
Predicted band size: 109 kDa
5% SDS PAGE
实验方案
数据表及文件
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SDS download
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Datasheet download
文献 (13)
ab95983 被引用在 13 文献中.
- Li Y et al. Endoplasmic reticulum stress increases exosome biogenesis and packaging relevant to sperm maturation in response to oxidative stress in obese mice. Reprod Biol Endocrinol 20:161 (2022). PubMed: 36411474
- Shriwas O et al. RRBP1 rewires cisplatin resistance in oral squamous cell carcinoma by regulating Hippo pathway. Br J Cancer 124:2004-2016 (2021). PubMed: 33762722
- Özkan N et al. ER - lysosome contacts at a pre-axonal region regulate axonal lysosome availability. Nat Commun 12:4493 (2021). PubMed: 34301956
- Luo HL et al. Hypomethylated RRBP1 Potentiates Tumor Malignancy and Chemoresistance in Upper Tract Urothelial Carcinoma. Int J Mol Sci 22:N/A (2021). PubMed: 34445467
- Anastasia I et al. Mitochondria-rough-ER contacts in the liver regulate systemic lipid homeostasis. Cell Rep 34:108873 (2021). PubMed: 33730569