概述

  • 产品名称Anti-RRAD抗体
    参阅全部 RRAD 一抗
  • 描述
    兔多克隆抗体to RRAD
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Cow, Orangutan
  • 免疫原

    Synthetic peptide conjugated to KLH derived from within residues 150 - 250 of Human RRAD.

    (Peptide available as ab95049.)

  • 阳性对照
    • This antibody gave a positive signal in Human skeletal muscle tissue lysate.

性能

应用

Our Abpromise guarantee covers the use of ab84109 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 µg/ml. Detects a band of approximately 33 kDa (predicted molecular weight: 33 kDa).

靶标

  • 功能May play an important role in cardiac antiarrhythmia via the strong suppression of voltage-gated L-type Ca(2+) currents. Regulates voltage-dependent L-type calcium channel subunit alpha-1C trafficking to the cell membrane (By similarity). Inhibits cardiac hypertrophy through the calmodulin-dependent kinase II (CaMKII) pathway. Inhibits phosphorylation and activation of CAMK2D.
  • 组织特异性Most abundantly expressed in the heart. Also found in the skeletal muscle and lung. Lesser amounts in placenta and kidney. Also detected in adipose tissue. Overexpressed in muscle of type II diabetic humans.
  • 序列相似性Belongs to the small GTPase superfamily. RGK family.
  • 细胞定位Cell membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • GTP binding protein RAD antibody
    • GTP-binding protein RAD antibody
    • RAD antibody
    • RAD_HUMAN antibody
    • RAD1 antibody
    • RAS (RAD and GEM) like GTP binding 3 antibody
    • Ras associated with diabetes antibody
    • Ras related associated with diabetes antibody
    • REM3 antibody
    • RRAD antibody
    see all

Anti-RRAD antibody 图像

  • Anti-RRAD antibody (ab84109) at 1 µg/ml + Human skeletal muscle tissue lysate - total protein (ab29330) at 10 µg

    Secondary
    Goat polyclonal to Rabbit IgG - H&L - Pre-Adsorbed (HRP) at 1/3000 dilution
    Developed using the ECL technique

    Performed under reducing conditions.

    Predicted band size : 33 kDa
    Observed band size : 33 kDa


    Exposure time : 3 minutes

Anti-RRAD antibody (ab84109)参考文献

ab84109 has not yet been referenced specifically in any publications.

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